Concurrent Transcranial Direct Current Stimulation and Gait Training in Parkinson's Disease

Parkinson's Disease Clinical Trial

Official title:

The Effect of Concurrent Transcranial Direct Current Stimulation and Gait Training on Gait Performance When Doing the Cognitive Dual-task in People With Parkinson's Disease

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04041661
• Other study ID #: 19MMHIS113e
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 1, 2019
• Est. completion date: August 31, 2020

Study information

• Verified date: August 2019
• Source: National Yang Ming University
• Contact: Yearu Yang, Ph.D
• Phone: +88628267279
• Email: yryang[@]ym.edu.tw
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To investigate the effect of concurrent transcranial direct current stimulation and gait training on gait performance when doing the cognitive dual-task in people with Parkinson's Disease.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: August 31, 2020
• Est. primary completion date: August 31, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years to 80 Years

Eligibility

Inclusion Criteria:

• Diagnosed with idiopathic PD

• Hoehn and Yahr stages I-III

• Mini Mental Status Examination (MMSE) score ? 24

• Could walk 10m independently with or without gait aid

Exclusion Criteria:

• Concurrent medication likely to affect mental performance

• tDCS contraindication

• Significant neurological, vestibular, visual disorders or psychiatric illness

• Musculoskeletal or cardiopulmonary disease

• Sensory system pathology

Related Conditions & MeSH terms

• Parkinson Disease
• Parkinson's Disease

Intervention

Other:
• Active tDCS plus gait training
Participants in experimental group will accept Active tDCS which combined with treadmill
• Sham tDCS plus gait training
Participants in control group will accept Sham tDCS which combined with treadmill

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
National Yang Ming University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Dual-task walking performance	To evaluate gait parameters while doing dual-task walking	Change from baseline at 4 weeks
Secondary	Single walking performance	To evaluate gait parameters while doing single walking	Change from baseline at 4 weeks
Secondary	Trail-making test A & B	To evaluate executive function	Change from baseline at 4 weeks
Secondary	Stroop color and word test-Chinese version	To evaluate executive function	Change from baseline at 4 weeks
Secondary	Digit span test	To evaluate executive function	Change from baseline at 4 weeks