MENTAL PRACTICE IN MOTOR LEARNING OF BRUSHING AND PARKINSON DISEASE

Parkinson's Disease Clinical Trial

Official title:

APPLICATION OF MENTAL PRACTICE IN MOTOR LEARNING OF BRUSHING ON PEOPLE WITH PARKINSON

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02738528
• Other study ID #: CAAE N°. 29242414.2.0000.5208
• Status: Completed
• Phase: N/A
• First received: April 8, 2016
• Last updated: April 8, 2016
• Start date: September 2014
• Est. completion date: October 2015

Study information

• Verified date: April 2016
• Source: Universidade Federal de Pernambuco
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

Parkinson's disease (PD) is characterized by dopaminergic neurons degeneration of the substantia nigra, in the midbrain, resulting in the presence of motor disorders, such as tremor, rigidity, bradykinesia, and postural instability. Researches have shown that mental rehearsal in learning motor skills through mental practice (MP), which associates the physical practice to somatosensory imagination to action, causes positive effects in several motor tasks, such as the speed of motion, muscle strength performance and accuracy. Thus, this study aims to report the effects of MP as a tooth brushing training strategy in people with Parkinson's disease. This project was approved by the Ethics Committee in Research with Human beings of UFPE and attempt to compare the presence of bacterial biofilm before and after 8 weeks of brushing through the mental practice training, based on O'Leary's index. The sample consisted of 35 people, divided into two groups: Intervention Group consists of 17 people with Parkinson's, in stages I to III of the disease, who underwent brushing orientation associated with PM, and the control group people without the disease, who received only orientation brushing. Then, the data were evaluated by factorial ANOVA 2x2 and post hoc Tukey test considering p <0.05. It was observed that after the intervention was a significant improvement of the control dental biofilm.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 35
• Est. completion date: October 2015
• Est. primary completion date: October 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 40 Years to 80 Years

Eligibility

Inclusion Criteria:

• Age between 40 and 80 years;

• Idiopathic PD Clinical Diagnostics according to the Bank of brain London;

• Patients in stages I to III according to Hoehn and Yahr;

• Satisfactory communicative and cognitive level checked by the Mini-Mental State Examination;

• Subject to satisfactory clinical, lying in his home in the care of relatives;

• Patients who possessed a sextant of the dental arch with teeth.

In the control group individuals without neurological disease were included: both sexes at ages similar to the group with PD, satisfactory health, active life, and natural teeth.

Exclusion Criteria:

• Another neurological disease associated with PD;

• Mioarticulares abnormalities in the upper limbs to prevent their use for independent brushing;

• Use of orthotic / prosthetic hand;

• Toothless in both dental arches.

In the control group were excluded individuals with mioarticulares abnormalities of the upper limbs; in use of orthotic / prosthetic hand; presenting any movement disorder in the upper limbs.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Parkinson Disease
• Parkinson's Disease

Intervention

Other:
• Mental practice and brushing guidance in patients with Parkinson Disease

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Universidade Federal de Pernambuco

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Dental biofilm	Based on O'Leary's index, the calculation was made dividing the number of surfaces stained by the total number of scanned surfaces, multiplied by 100.	8 weeks	Yes