Parkinson's Disease Clinical Trial
Official title:
Haptoglobin Phenotype and Smoking: Effects on Iron Levels in Parkinson's Disease
This is a case/control epidemiology study to identify what are the iron-metabolism abnormalities in Parkinson's disease (PD) patients, and risk factors relevant to PD predisposition.
A total of 342 participants, 100 PD patients and 242 age- and gender matched controls, were
included in the study. All study participants were seen for one study visit in the morning
at one of two Bastyr University Clinics in the Seattle area. Study participants were fasting
at the time of the visit. During the study visit, participants donated a blood sample for
the blood tests and complete an epidemiology questionnaire.
A subset of 51 of the study participant who were seen for the visit at Bastyr University,
underwent brain scan and Magnetic Resonance Imaging (MRI), at the University of Washington
Department of Radiology. The MRI part of the study aims at estimating brain iron levels.
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Observational Model: Case Control, Time Perspective: Cross-Sectional
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