Effect of Opicapone at Steady State on Warfarin Pharmacokinetics

Status Completed

Clinical Trial Summary

Single-centre, open-label, fixed-sequence design consisting of 2 periods separated by a washout period of at least 14 days.

Clinical Trial Description

Single-centre, open-label, fixed-sequence design consisting of 2 periods separated by a washout period of at least 14 days. In Period 1, a single dose of 25 mg warfarin was administered alone. In Period 2, subjects received 475 mg OPC, on Day 1 and D2 followed by 50 mg OPC once daily for 5 days (D3 to D7). On D8, 50 mg OPC was administered with a single dose of 25 mg warfarin. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02305030
Study type	Interventional
Source	Bial - Portela C S.A.
Contact
Status	Completed
Phase	Phase 1
Start date	March 2014
Completion date	May 2014

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