Parkinson's Disease Clinical Trial
Parkinson's disease (PD) is a progressive degenerative disease of central nervous systems
deficit. The clinical symptoms of Parkinson's disease include the following motor tasks:
difficult in initiating movement, performing rhythmic movement or serial movement, the
ability of learning motor movement is also affected. The primary treatment for Parkinson's
disease is medical treatment; surgery is used if in need. Rehabilitation such as physical
therapy, which aims to improve patient's quality of life and functions, is a non-invasive
treatment and value for PD patients. Auditory cue is a technique that widely applied on
training patients with Parkinson's disease, and some researches revealed that auditory
cueing could improve motor performance. However, the mechanism under this treatment
technique is still unknown.
This study is to investigate the effect of auditory cueing on rhythmic finger movement in
patients with Parkinson's disease. To investigate the mechanism under auditory cueing,
neurophysiological data such as motor cortex excitability and blood flow in cortical cortex
will be obtained by using Transcranial magnetic stimulation (TMS) and near infrared
spectroscopy (NIRS).
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
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