Parkinson's Disease Clinical Trial
Official title:
A Randomized Controlled Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease
This randomized, controlled trial (RCT) evaluates the benefits of memory and problem solving
training compared to supportive therapy in individuals with Parkinson's Disease with Mild
Cognitive Impairment (MCI) and their support persons. Participants will be randomly assigned
to receive memory and problem solving training or supportive therapy for 2-months. A 6-month
follow up evaluation will establish if benefits remain over time. Impact of these therapies
on thinking abilities, physical health, and patient and support person ratings of thinking
skills, mood and quality of life will be evaluated. The memory and problem solving training
is hypothesized to result in greater improvements and/or stability of function on
neuropsychological tests of attention, working memory, learning, and memory skills compared
to the supportive therapy condition. Both conditions are hypothesized to result in improved
mood and quality of life ratings.
Results from this study will determine whether memory and problem solving therapies and
supportive therapy are easily used by and beneficial for individuals with Parkinson's
Disease and Mild Cognitive Impairment. If positive benefit is observed, information from
this study will be used to further optimize these therapies for larger trials designed to
evaluate the value of the therapies for individuals with Parkinson's Disease and their
support persons.
The memory and problem solving training consists of a day calendar manual and note taking system and problem solving techniques. The supportive therapy offers patients and support persons the opportunity to discuss and reflect upon both Parkinson's Disease and non-Parkinson's Disease related problems. ;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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