Parkinson's Disease Clinical Trial
Official title:
Efficacy and Safety of BIA 9-1067 in Idiopathic Parkinson's Disease Patients With "Wearing-off" Phenomenon Treated With Levodopa Plus a Dopa Decarboxylase Inhibitor (DDCI): a Double-blind, Randomised, Placebo-controlled, Parallel-group, Multicentre Clinical Study.
Parkinson's disease (PD) is a neurodegenerative disorder of unknown aetiology with an
estimated incidence of 4.5-16/100,000 persons/year.
BIA 9-1067 is currently being developed by BIAL (Portela & Cª,S.A.) to be used in addition
to L-DOPA (Levodopa) /carbidopa or L-DOPA (Levodopa) / preparations in PD patients.
Promising results have been obtained for BIA 9-1067 in previous studies.
This study aims to demonstrate the efficacy and safety of BIA 9-1067 used in addition to
L-DOPA/DDCI to control the "wearing-off" phenomenon in patients with PD.
DDCI (DOPA decarboxylase inhibitors): benserazide and carbidopa
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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