Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD

Parkinson's Disease Clinical Trial

Official title:

Characterizing Mechanisms of Fronto-Subcortical Dysfunction: A Comparison Between Parkinson's Disease and Obsessive-Compulsive Disorder

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT00790634
• Other study ID #: SHEBA-08-5473-SH-CTIL
• Status: Not yet recruiting
• Phase: N/A
• First received: November 12, 2008
• Last updated: November 12, 2008
• Start date: December 2008
• Est. completion date: December 2011

Study information

• Verified date: November 2008
• Source: Sheba Medical Center
• Contact: Sharon Hassin, MD
• Phone: 97235305791
• Email: shassin[@]post.tau.ac.il
• Is FDA regulated: No
• Health authority: Israel: Ministry of Health
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive disorder, by examining performance on cognitive tasks involving cognitive flexibility, decision-making, and attentional bias.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: December 2011
• Est. primary completion date: December 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 16 Years to 85 Years

Eligibility

Inclusion Criteria:

• idiopathic PD or

• OCD

• for control group - age-matched to study groups

Exclusion Criteria:

• psychotic symptoms (past or present)

• head injury with loss of consciousness

• other neurological conditions (excepting PD in PD group)

• for OCD group - use of dopaminergic medications

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Compulsive Behavior
• Obsessive-Compulsive Disorder
• Parkinson Disease
• Parkinson's Disease

Locations

Country	Name	City	State
n/a

Sponsors (3)

Lead Sponsor	Collaborator
Sheba Medical Center	Israel Science Foundation, University of Haifa