Clinical Trials Logo

Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT06456840
Other study ID # 24277
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date July 15, 2024
Est. completion date December 30, 2024

Study information

Verified date June 2024
Source Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Contact MÜRVET ARDA KÖROGLU, MD
Phone 00905353251323
Email arda.murvet@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Parkinson's disease was first described in history in 1817 by James Parkinson in his monograph "An essay on swinging palsy", and today it is the 2nd most common neurodegenerative disease after Alzheimer's, affecting approximately 6.1 million people. Its main histopathological feature is the decrease in dopaminergic secretion in the basal ganglia and there are three cardinal findings: Bradykinesia, Tremor, Rigidity. Although joint and skeletal deformities are seen in approximately 70% of Parkinson's patients, they are not adequately evaluated and cause significant functional disability and chronic pain, independent of motor symptoms.Musculoskeletal pathologies seen in Parkinson's patients can be classified as: musculoskeletal pain, articular problems, postural problems and bone mineralization defects. The shoulder girdle is a joint with complex and delicate function, consisting of four joints (glenohumeral, sternoclavicular, acromioclavicular and scapulothoracic), supporting muscles and periarticular ligaments, which seriously affects the patient's quality of daily life and function. Although magnetic resonance imaging (MRI) is the best imaging tool in the diagnosis of musculoskeletal system pathologies, it is quite sensitive to artifact-forming motion. Ultrasound (US) imaging is widely used in the evaluation of rotator cuff muscles, biceps muscle and glenohumeral joint pathologies and has many advantages over MRI, such as providing fast, cheap and dynamic imaging. Although many studies have proven that shoulder girdle musculoskeletal pathologies such as bicipital tendinitis, m.supraspinatus tendinosis, subacromial/subdeltoid bursitis, subacromial impingement syndrome, and adhesive capsulitis are seen more frequently in Parkinson's patients by ultrasonographic imaging, these shoulder girdle pathologies seen in Parkinson's patients are more common. The risk factors for pathologies have not been defined. In this study, we aimed to determine the ultrasonographic findings and risk factors of shoulder pathologies in Parkinson's patients and to investigate the effects of shoulder pathologies on quality of daily life, physical activity, falls and balance.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 160
Est. completion date December 30, 2024
Est. primary completion date October 15, 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 50 Years and older
Eligibility Inclusion Criteria: Group1 - Being diagnosed with Parkinson's according to the Movement Disorders Society diagnostic criteria - Being over 50 years old - Being in the Hoehn & Yahr stage I-IV range - Identification of pain in at least one shoulder (VAS>3) - Agreeing to participate in the study - Being literate Group2 - Being diagnosed with Parkinson's according to the Movement Disorders Society diagnostic criteria - Being over 50 years old - Being in the Hoehn & Yahr stage I-IV range - No pain in both shoulders (VAS: 0) - Agreeing to participate in the study - Being literate Group 3 - Describe pain >3 on the visual pain scale in any shoulder - Being over 50 years old - Becoming literate - Agreeing to participate in the study Group 4 1. Not defining pain with a score of 0 on the visual pain scale in both shoulders 2. Being over 50 years old 3. Being literate 4. Agreeing to participate in the study Exclusion Criteria: - Scoring less than 24 points in the Mini Mental Test - Having had a myocardial infarction - Having had a cerebrovascular accident - Having a rheumatological disease - Known endocrine disease (Diabetes Mellitus, Hypo/hyperthyroidism) - Cervical disc herniation defining radiculopathy - Active trigger point palpated in the shoulder girdle muscles - Having had any shoulder surgery - Concomitant history of active systemic inflammatory disease, active infection and active malignancy - Physical Therapy modalities have been applied in the last 6 months - Having had an interventional procedure performed on the shoulder area within the last 6 months - Using medications that may cause tendinopathy (Fluoroquinolines)

Study Design


Related Conditions & MeSH terms


Intervention

Diagnostic Test:
ULTRASOUND
Measurements will be made in musculoskeletal system ultrasonography by an international Medicine and Rehabilitation assistant physician using images obtained with the Sonosite M-Turbo device using the ImageJ program. During the measurements, the patient and the patient will be face to face and the device will be placed postero-laterally. Five standard window spacings will be used for the shoulder attachment. These are: anterior transverse, anterior longitudinal, lateral longitudinal, lateral transverse, posterior transverse.

Locations

Country Name City State
Turkey Sultan 2. Abdulhamid Han Training and Research Hospital Istanbul

Sponsors (1)

Lead Sponsor Collaborator
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey

Country where clinical trial is conducted

Turkey, 

Outcome

Type Measure Description Time frame Safety issue
Primary USG FINDINGS Measurements will be made by a Physical Medicine and Rehabilitation assistant physician experienced in musculoskeletal system ultrasonography, using the images obtained with the Sonosite M-Turbo device using the ImageJ program. During the measurements, the device will be positioned on the postero-lateral side of the patient while the patient and the practitioner are face to face. Five standard viewing windows will be used for the shoulder joint. These are: anterior transverse, anterior longitudinal, lateral longitudinal, lateral transverse, posterior transverse. ONE MONTH
See also
  Status Clinical Trial Phase
Completed NCT05415774 - Combined Deep Brain Stimulation in Parkinson's Disease N/A
Recruiting NCT04691661 - Safety, Tolerability, Pharmacokinetics and Efficacy Study of Radotinib in Parkinson's Disease Phase 2
Active, not recruiting NCT05754086 - A Multidimensional Study on Articulation Deficits in Parkinsons Disease
Completed NCT04045925 - Feasibility Study of the Taïso Practice in Parkinson's Disease N/A
Recruiting NCT04194762 - PARK-FIT. Treadmill vs Cycling in Parkinson´s Disease. Definition of the Most Effective Model in Gait Reeducation N/A
Completed NCT02705755 - TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH) Phase 2
Terminated NCT03052712 - Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies N/A
Recruiting NCT05830253 - Free-living Monitoring of Parkinson's Disease Using Smart Objects
Recruiting NCT03272230 - Assessment of Apathy in a Real-life Situation, With a Video and Sensors-based System N/A
Recruiting NCT06139965 - Validity and Reliability of the Turkish Version of the Comprehensive Coordination Scale in Parkinson's Patients
Completed NCT04580849 - Telerehabilitation Using a Dance Intervention in People With Parkinson's Disease N/A
Completed NCT03980418 - Evaluation of a Semiconductor Camera for the DaTSCAN™ Exam N/A
Completed NCT04477161 - Effect of Ketone Esters in Parkinson's Disease N/A
Completed NCT04942392 - Digital Dance for People With Parkinson's Disease During the COVID-19 Pandemic N/A
Terminated NCT03446833 - LFP Beta aDBS Feasibility Study N/A
Completed NCT03497884 - Individualized Precise Localization of rTMS on Primary Motor Area N/A
Completed NCT05538455 - Investigating ProCare4Life Impact on Quality of Life of Elderly Subjects With Neurodegenerative Diseases N/A
Recruiting NCT04997642 - Parkinson's Disease and Movement Disorders Clinical Database
Completed NCT04117737 - A Pilot Study of Virtual Reality and Antigravity Treadmill for Gait Improvement in Parkinson N/A
Recruiting NCT03618901 - Rock Steady Boxing vs. Sensory Attention Focused Exercise N/A