Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms

Status Not yet recruiting

Clinical Trial Summary

This study is a double blind comparative study exploring the neural underpinnings of taVNS modulating PD motor deficits. We hypothesize that taVNS might improve PD motor deficits by regulating the balance between excitation and inhibition in the primary motor cortex.

Clinical Trial Description

Patients in the Experimental group underwent fourteen consecutive daily sessions of transcutaneous auricular vagus nerve stimulation (taVNS, twice daily, 30 minutes each time) , whereas patients in the sham stimulation group underwent fourteen consecutive daily sessions of sham taVNS with the electrodes were fixed at the left earlobe . Assessments of motor symptoms and cortical activity (using Functional near-infrared spectroscopy and Transcranial magnetic stimulation) were performed two times: at baseline, one day post intervention. ;

Study Design

Related Conditions & MeSH terms

Parkinson Disease

Clinical Trial Details

NCT number	NCT06409338
Study type	Interventional
Source	The First Affiliated Hospital with Nanjing Medical University
Contact	Zhang Kezhong
Phone	13770840575
Email	kezhong_zhang1969@126.com
Status	Not yet recruiting
Phase	N/A
Start date	May 2024
Completion date	September 2024

View Details

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