Classical Guitar for Parkinson's Disease

Parkinson Disease Clinical Trial

Official title:

CAPO: Classical Guitar to Alleviate Parkinson's Disease Symptom Onus

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05917704
• Other study ID #: STUDY00017748
• Status: Recruiting
• Phase: N/A
• Start date: June 6, 2023
• Est. completion date: February 1, 2024

Study information

• Verified date: June 2023
• Source: University of Washington
• Contact: Christopher Adams, MS, MD
• Phone: 206-616-5207
• Email: caadams1[@]uw.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to understand if training Parkinson's disease patients in classical guitar will improve motor function, mood, and quality of life. While medication has been found to be effective for many Parkinson's disease patients, many patients still have symptoms. Previous studies have found that music and rhythm-based activities can help Parkinson's disease symptoms. A previous study looked at the effect of playing classical guitar on Parkinson's disease symptoms. They found positive changes in Parkinson's disease symptoms that lasted for 6 weeks after the study ended. Further, there were positive changes in depression, anxiety, and quality of life.

Description:

Subjects will be asked to take part in classical guitar lessons once a week for six weeks and physical therapy once a week for six weeks. There will be 40 people enrolled in the study. Twenty people will have classical guitar lessons first and physical therapy second. The other twenty people will have physical therapy first and classical guitar lessons second. The study will last a total of 12 weeks. Each session will last 1-2 hours. Sessions will be held at the Northwest Chapter headquarters of the American Parkinson's Disease Association.

Examples of the types of activities subjects will do during the physical therapy sessions include finger exercises, tasks with both hands, tasks while standing, and tasks while walking.

Examples of the types of activities you will do during the classical guitar lessons include playing chords and songs on the guitar.

Subjects will have physical exams and complete questionnaires at the beginning of the study, at six weeks, and at the end of the study.

If subjects have Apple watches, they will be asked to download an application called StrivePD on their watch and iPhone. StrivePD is an application that allows subjects to keep track of their Parkinson's disease symptoms or set medication reminders, for example. When used with an Apple watch, it can automatically record symptoms like tremors. During this study, the StrivePD application will only be used to collect data about what percentage of the day they have tremors and how much they sleep.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: February 1, 2024
• Est. primary completion date: December 12, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years to 90 Years

Eligibility

Inclusion Criteria:

• 50-90 years old

• Diagnosis with Parkinson's disease by a Movement Disorder specialist

Exclusion Criteria:

• Professional musician or formal music training

• Inability to play a classical guitar physically

• Inability to follow instruction

• Receiving physical therapy at the time of the study

• Unable to attend all sessions of study

Related Conditions & MeSH terms

• Parkinson Disease

Intervention

Other:
• Guitar then physical therapy
See arm/group descriptions
• Physical therapy then guitar
See arm/group descriptions

Locations

Country	Name	City	State
United States	Northwest Chapter of the American Parkinson Disease Association	Seattle	Washington

Sponsors (1)

Lead Sponsor	Collaborator
University of Washington

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in the motor subscore of the Movement Disorder Society Unified Parkinson's Disease Rating Scale Motor Subscale	Change in Parkinson's disease rating scale, range 0-32, higher score means more severe Parkinson's disease symptoms	Baseline, 6 weeks, 12 weeks
Secondary	Change in Parkinson's disease Questionnaire-39	Change in scale for quality of life, range 0-100, higher means worse Parkinson's disease symptoms	Baseline, 6 weeks, 12 weeks
Secondary	Change in percent of day with tremor	Change in percent of day with tremor from apple watch	Baseline, 6 weeks, 12 weeks
Secondary	Change in Beck Depression Inventory-II	depression scale, range 0-63, higher score means worse depression	Baseline, 6 weeks, 12 weeks
Secondary	Change in Apathy evaluation scale total score	Change in apathy scale, range 18-72, higher scores means worse apathy	Baseline, 6 weeks, 12 weeks
Secondary	Change in American Parkinson's disease Association symptom tracker score	Change in Parkinson's disease symptom tracker, range 0-50, higher scores means worse symptoms	Baseline, 6 weeks, 12 weeks
Secondary	Change in hours of sleep	Change in hours of sleep measured from apple watch data	Baseline, 6 weeks, 12 weeks