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Continuous Theta Burst Stimulation as Potential Biomarker of Levodopa-induced Dyskinesias in Parkinson's Disease

Parkinson Disease Clinical Trial

Official title:
Role of Continuous Theta Burst Stimulation as Potential Biomarker of Levodopa-induced Dyskinesias in Patients With Parkinson's Disease.

Clinical Trial Summary

The primary endpoint of the study is to identify a neurophysiological biomarker (absence of synaptic depotentiation at primary motor cortex , measured as change in the amplitude of motor evoked potentials recorded at the dorsal first interosseus muscle after administration of neurophysiological cTBS depotentiation protocol) as predictor of the development of Levodopa-induced dyskinesia in patients with Parkinson's disease.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05795088
Study type Interventional
Source Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Contact Francesco Bove, MD
Phone +390630156433
Email francesco.bove@policlinicogemelli.it
Status Recruiting
Phase N/A
Start date June 16, 2022
Completion date February 28, 2025
View Details
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