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The Effect and Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation on Gait Impairments in PD

Parkinson Disease Clinical Trial

Official title:
Study on the Therapeutic Effect and Brain Mechanism of Transcutaneous Vagal Nerve Stimulation on Gait Impairments in Parkinson's Disease

Clinical Trial Summary

This study is a double blind comparative study examining the effectiveness of the transcutaneous auricular vagus nerve stimulation treatment on Parkinson's disease patients . We hypothesize that treatment using transcutaneous auricular vagus nerve stimulation will improve gait impairments and cortical activity in Parkinson's disease patients.

Clinical Trial Description

Patients in the Experimental group underwent seven consecutive daily sessions of transcutaneous auricular vagus nerve stimulation (taVNS, twice daily, 30 minutes each time) , whereas patients in the sham stimulation group underwent seven consecutive daily sessions of sham taVNS. Assessments of gait function, motor symptoms and cortical activity (using Functional near-infrared spectroscopy) were performed two times: at baseline, one day post intervention. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05561348
Study type Interventional
Source The First Affiliated Hospital with Nanjing Medical University
Contact Zhang Kezhong
Phone 13770840575
Email kezhong_zhang1969@126.com
Status Recruiting
Phase N/A
Start date August 1, 2022
Completion date January 31, 2023
View Details
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