Effects of Physical-Cognitive Training With Different Task Models in Parkinson's Disease With Mild Cognitive Impairment

Parkinson Disease Clinical Trial

Official title:

Effects of Physical-Cognitive Training With Different Task Models on Dual-Task Walking in Parkinson's Disease With Mild Cognitive Impairment

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05172661
• Other study ID #: 202109095RINA
• Status: Completed
• Phase: N/A
• Start date: November 26, 2021
• Est. completion date: September 30, 2022

Study information

• Verified date: January 2023
• Source: National Taiwan University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The present study will characterize exercise model effects (integrated model vs. consecutive model) of physical-cognitive exercise on dual-task walking control in Parkinson's disease with mild cognitive impairment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 27
• Est. completion date: September 30, 2022
• Est. primary completion date: June 30, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years and older

Eligibility

Inclusion Criteria:

• a diagnosis of idiopathic Parkinson's disease

• have decreased cognitive functions but do not interfere with functional independence

• Montreal Cognitive Assessment (MoCA): 21-25

• able to walk independently without walking devices for at least 10 meters and with the ability to turn 180°

Exclusion Criteria:

• a diagnosis of dementia

• other diseases that may influence cognitive functions or walking performance

• a history of brain surgery

• modification of the medication during the exercise intervention

Related Conditions & MeSH terms

• Cognitive Dysfunction
• Mild Cognitive Impairment
• Parkinson Disease

Intervention

Behavioral:
• Integrated physical-cognitive training
Perform a postural task and a cognitive task at the same time (dual-task model) 70 minutes/session*2 sessions/week*6 weeks
• Consecutive physical-cognitive training
Perform a postural task and a cognitive task separately for identical durations 70 minutes/session*2 sessions/week*6 weeks

Locations

Country	Name	City	State
Taiwan	National Taiwan University	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change from baseline dual-task walking performance at 8 weeks		8 weeks
Primary	Fall frequency		20 weeks
Primary	Change from baseline Montreal Cognitive Assessment (MoCA) score at 8 weeks	MoCA: 0-30 points, higher scores mean a better outcome	8 weeks