Parkinson´s Disease, Aerobic Exercise and Photobiomodulation

Parkinson Disease Clinical Trial

— PDAERPBM  

Official title:

Parkinson´s Disease, Aerobic Exercise and Photobiomodulation: a Randomised Controlled Trial

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT05152706
• Other study ID #: No. 295/19
• Status: Active, not recruiting
• Phase: N/A
• Start date: January 10, 2022
• Est. completion date: June 10, 2023

Study information

• Verified date: November 2022
• Source: University of Oviedo
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the present study was to assess the effects of a combined therapy of aerobic exercise and transcranial photobiomodulation upon the cardinal motor sympomts of Parkinson´s disease of a group of Parkinson´s disease patients. It was hypothesized that aerobic exercise and transcranial photobiomodulation would yield significant benefits in the cardinal motor sympomts of the illness.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 32
• Est. completion date: June 10, 2023
• Est. primary completion date: June 10, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Diagnosis with idiopathic PD and rated 1-2 on the Hoehn and Yahr Scale.

• No type of dementia as assessed by the mini-mental state examination.

• Able to stand for 2 min without assistance.

• Able to walk 10 m without assistance.

Exclusion Criteria:

• Individuals were excluded if they suffered a neurological disease other than PD, if the subject has an implant of any kind in the head (e.g., stent, clipped aneurysm, embolized arteriovenous malformation, implantable shunt - Hakim valve) or if they did not meet the eligibility criteria.

Related Conditions & MeSH terms

• Parkinson Disease

Intervention

Other:
• Aerobic training
Cycling at the aerobic intensity
• Photobiomodulation
Photons therapy

Locations

Country	Name	City	State
Spain	Department of Physical Education and Sport, University of León	León	Castilla Y León

Sponsors (1)

Lead Sponsor	Collaborator
University of Oviedo

Country where clinical trial is conducted

Spain, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	MDS-UPDRS	The motor portion of the Movement Disorder Society-Unified Parkinson´s (MDS-UPDRS, the minimum and maximum values are 0 and 72, respectively and the higher score, the worse patient condition)	6 months
Secondary	DASH	The disabilities of the arm, shoulder and hand (DASH, the minimun and maximum values are 0 and 190, respectively and the higher score, the worse patient condition)	6 months
Secondary	Static posturography	The centre of pressure (CoP) parameters (these CoP parameters; Length, in mm, Area in mm2 and Speed, Xspeed and Yspeed in m/s will be combined to report the static posturography)	6 months
Secondary	TMWT	10 meters walking test (speed in seconds)	6 months
Secondary	TUG	Time up Go Test (speed in seconds)	6 months
Secondary	Grip strength	Grip strength in kg	6 months