Movement Disorders Analysis Using a Deep Learning Approach

Parkinson Disease Clinical Trial

Official title:

Movement Disorders Analysis Using a Deep Learning Approach

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04974034
• Other study ID #: CLEA-2019-83
• Status: Completed
• Start date: June 1, 2019
• Est. completion date: December 31, 2020

Study information

• Verified date: July 2021
• Source: Hospital Avicenne
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Bradykinesia is a key parkinsonian feature yet subjectively assessed by the MDS-UPDRS score, making reproducible measurements and follow-up challenging.

In a Movement Disorder Unit, the investigators acquired a large database of videos showing parkinsonian patients performing Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III protocols.

Using a Deep Learning approach on these videos, the investigators aimed to develop a tool to compute an objective score of bradykinesia from the three upper limb tests described in the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: December 31, 2020
• Est. primary completion date: November 18, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age > 18 years

Exclusion Criteria:

• Refusal of participation

Related Conditions & MeSH terms

• Akinesia
• Bradykinesia
• Hypokinesia
• Movement Disorders
• Parkinson Disease
• Parkinsonian Disorders
• Parkinsonian Syndrome

Locations

Country	Name	City	State
France	Hospital Avicenne	Bobigny	Seine Saint Denis

Sponsors (1)

Lead Sponsor	Collaborator
Hospital Avicenne

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III score	Automatic Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III for hand bradykinesia including the three following specific tasks (finger tapping, hand movements and pronation-supination movements of hand).; The minimum score is 0. The maximum score is 12 Higher scores mean wors outcome	1 day