Parkinson Disease Clinical Trial
— METACTIONOfficial title:
Role of Basal Ganglia and Thalamus in Perceptual Consciousness and Metacognition
Verified date | April 2022 |
Source | University Hospital, Grenoble |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The term perceptual awareness refers to subjective experience... or the phenomenology associated with the processing of a sensory stimulus. The term metacognition refers to our ability of introspection, knowledge and control of our own cognitive processes. The objective of this research is to establish the contribution of the basal ganglia and thalamus to the perceptual awareness and meta-cognition, using deep brain stimulation coupled with electroencephalography.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | November 2025 |
Est. primary completion date | November 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Major patient in need of brain stimulation therapy for motor disorders (Parkinson's disease, tremor, dystonia) or psychiatric disorders (OCD). - Outpatient or inpatient follow-up - Fluent in French and able to understand the study procedures - informed consent - Patient affiliated to social security - Written agreement to participate in the patient's study - Intellectual abilities compatible with the performance of cognitive or motor tasks Exclusion Criteria: - Persons referred to in Articles L1121-5 to L1121-8 of the CSP (pregnant women, parturient women, mothers, etc.) who is breastfeeding, person deprived of liberty by judicial or administrative decision, person subject to a legal protection measure - Patients in whom transient cessation of stimulation is not tolerated - Subject in period of exclusion from another study - Subject cannot be contacted in case of emergency - Subject under administrative or judicial supervision |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Grenoble |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Behavioral effect of DBS on confidence | Confidence in correct and incorrect responses will be compared on and off stimulation | by fall 2024 | |
Secondary | Effect of DBS on EEG markers of confidence | EEG correlates of confidence in correct and incorrect responses will be compared on and off stimulation | by fall 2024 |
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