Parkinson Disease Clinical Trial
Official title:
Speech-in-Noise Treatments to Improve Hypophonia in Everyday Social Contexts for Individuals With Parkinson's Disease
Hypophonia, or reduced speech intensity, is the most prevalent speech symptom in Parkinson's disease (PD) and often leads to significant difficulty communicating in most social situations. Behavioural treatments for hypophonia can be temporarily effective but many individuals fail to retain and transfer improvements beyond the context of the speech clinic. The present study will address the transfer of treatment problem using two new treatment programs. Both treatments focus on improving speech intensity during conversations in different social contexts and a wide range of background noise conditions. The Speech-in-Noise (SIN) treatment program involves training higher speech intensity during variable levels of background noise while receiving real-time intensity feedback from a speech therapist. The second treatment, the Speech-to-Noise Feedback (SNF) device treatment program, involves using a wearable SNF device to provide feedback about an ideal target speech-to-noise level in a wide range of background noise conditions. Forty individuals with PD and their communication partners (i.e. spouse) will be randomly assigned to one of the two treatment programs. To evaluate the effectiveness of the treatments, a wearable recording device will measure daily conversational speech intensity and background noise for 7 consecutive days before, 1 week after, and 12 weeks after treatment.
Status | Not yet recruiting |
Enrollment | 80 |
Est. completion date | December 2021 |
Est. primary completion date | September 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 45 Years to 85 Years |
Eligibility |
Inclusion Criteria: - Diagnosed with idiopathic PD and hypophonia by a neurologist at least 6 months prior to participation. - Stabilized on antiparkinsonian medication. - Good general health. - 45-85 years old. - Pass a 50 dB hearing screening and cognitive screening (>20/30 on MOCA). - Proficient enough in English to participate in speech testing. Exclusion Criteria: - History of stroke or an additional neurological or motor control disorder. - History of speech impairment that is unrelated to PD. |
Country | Name | City | State |
---|---|---|---|
Canada | LawsonHRI | London | Ontario |
Lead Sponsor | Collaborator |
---|---|
Lawson Health Research Institute |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | speech-to-noise ratio | Average speech-to-noise ratio obtained from long-term conversation samples | 7 days | |
Secondary | communication effectiveness ratings | Self-ratings of communication effectiveness using an 8-item questionnaire. | 7 days | |
Secondary | communication participation ratings | Self-ratings of communication participation using a 28 item questionnaire. | 7 days |
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