Alternating DBS for Stepping Control in Parkinson's Disease

Status Recruiting

Clinical Trial Summary

Parkinson's disease (PD) is a disabling, progressive condition characterised by severe problems with movement for which medical treatment in the longer term can be unsatisfactory. Deep brain stimulation (DBS) is a treatment, which directly stimulates the nerve cells affected inside the brain to help overcome the difficulties with movement. Classically, DBS stimulates in a manner that is constant. Many patients develop severe problems with walking, so-called freezing of gait, which can be unresponsive to constant DBS. In this study the investigators will test if left-right alternating DBS helps to improve gait problems by potentially promoting left-right alternating up- and down-modulated brain activity, which was found during walking in a previous study. The investigators will test if alternating DBS improves the ability to adjust walking speed and to walk freely compared to constant DBS.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Parkinson Disease

Clinical Trial Details

NCT number	NCT04047498
Study type	Interventional
Source	University of Oxford
Contact	Peter Brown, MD
Phone	01865 572 482
Email	peter.brown@ndcn.ox.ac.uk
Status	Recruiting
Phase	N/A
Start date	May 1, 2019
Completion date	November 2020

View Details

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