Study of OXB-102 (AXO-Lenti-PD) in Patients With Bilateral, Idiopathic

Status Terminated

Clinical Trial Summary

This study consists of two parts. Part A will evaluate the safety and tolerability of multiple doses of OXB-102 (AXO-Lenti-PD) in participants with Parkinson's disease. Part B will assess the safety and efficacy of the selected dose of OXB-102 in participants with Parkinson's disease.

Clinical Trial Description

This study consists of two parts. Part A is an open-label dose-escalation phase in which participants are enrolled in cohorts and will receive one of approximately three escalating doses of OXB-102 (AXO-Lenti-PD). Part B is a randomized, double-blind phase in which participants will be randomized to either an active group receiving the selected dose from Part A, or to a control group receiving an imitation surgical procedure (ISP). ;

Study Design

Related Conditions & MeSH terms

Parkinson Disease

Clinical Trial Details

NCT number	NCT03720418
Study type	Interventional
Source	Sio Gene Therapies
Contact
Status	Terminated
Phase	Phase 1/Phase 2
Start date	October 17, 2018
Completion date	April 12, 2022

View Details

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Study of OXB-102 (AXO-Lenti-PD) in Patients With Bilateral, Idiopathic Parkinson's Disease — SUNRISE-PD

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms