Parkinson Disease Clinical Trial
— RTsAsMIRTOfficial title:
Relationship Between Dopaminergic Asymmetric Degeneration and Attentional Resources in Parkinson's Disease.
Verified date | May 2018 |
Source | Ospedale Generale Di Zona Moriggia-Pelascini |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The researchers aimed to investigate the relationship between the asymmetric dopaminergic degeneration and the attentional resources in a group of patients with Parkinson's disease (PD).
Status | Completed |
Enrollment | 100 |
Est. completion date | August 1, 2017 |
Est. primary completion date | August 1, 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 40 Years to 85 Years |
Eligibility |
Inclusion Criteria: - Stage 2.5-3 according to the Hoehn and Yahr scale (H&Y); - Stable pharmacological treatment for the last 6 weeks before the enrolment and during the hospitalization; - Mini Mental State Examination (MMSE) = 24; - No evidences of dysexecutive syndrome. Exclusion Criteria: - Any focal brain lesion detected in brain imaging studies (CT or MRI) performed in the previous 12 months; - Drug-induced dyskinesias; - Disturbing resting and/or action tremor, corresponding to scores 2-4 in the specific items of UPDRS III; - Behavioral disturbances (evaluated with Neuropsychiatric Inventory); - Visual and auditory dysfunctions according to the general clinical evaluation and medical history; - Equivocal report about the side of disease onset or bilateral motor involvement. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Ospedale Generale Di Zona Moriggia-Pelascini |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Visual Reaction Times (V RTs) | Visual Reaction Times | 4 weeks | |
Primary | Auditory Reaction Times (A RTs) | Auditory Reaction Times | 4 weeks | |
Primary | Multiple Choices RTs (MC RTs) | Multiple Choices RTs | 4 weeks | |
Secondary | Unified Parkinson's Disease Rating Scale (UPDRS) | Unified Parkinson's Disease Rating Scale | 4 weeks | |
Secondary | Timed Up and Go Test (TUG) | Timed Up and Go Test | 4 weeks |
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