Lateral Postural Inclination in Parkinson's Disease : Involvement of the Basal Ganglia ? — IPOLAP  

Parkinson Disease Clinical Trial

Official title: Lateral Postural Inclination in Parkinson's Disease : Involvement of the Basal Ganglia ?

Status Terminated

Clinical Trial Summary

The objective of this study is to assess the origins of lateral postural inclination presented by some Parkinson disease's patients.

Several mechanisms could cause lateral postural inclination. Available data allow to suggest three hypothesis: (troubles of tonus, perception of vertical perturbation, trouble of perception of corporal axis

Clinical Trial Description

Inclusion Criteria:

• 30 to 75 years old patient

• Parkinson disease's diagnosed since 5 years

• Treated by deep brain stimulation

• Patient with at least 6 degree lateral deviation

• Without vestibular troubles nor peripheral sensorial trouble.

Exclusion Criteria:

• Dementia (Mattis < 130 ou MMS <24), or severe depressive episode according to DSM IV-R criteria

• Camptocormia or incompatible anteflexion with the dispositive of measure device

• Pregnant woman, nursing mother ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Parkinson Disease

• NCT number: NCT02704910
• Study type: Interventional
• Source: University Hospital, Grenoble
• Status: Terminated
• Phase: N/A
• Start date: January 2012
• Completion date: June 2015