Effects of Vitamin D in Parkinson's Disease (PD)

Parkinson Disease Clinical Trial

Official title: The Effects of Vitamin D on Balance in Persons With PD

Status Completed

Clinical Trial Summary

A trial to measure the effects of vitamin D (versus a placebo) on balance, gait, falls, strength, and cognition in persons with Parkinson's disease.

Clinical Trial Description

The proposed study is a randomized, double-blinded, placebo controlled intervention trial to measure the effects of vitamin D at (10,000IU/day) versus placebo on balance and falls in Parkinson's disease. The investigators will measure static, dynamic, and ambulatory balance, as well as strength, falls, and cognition before and after 16 weeks of therapy. Dynamic posturography will be used to measure static and ambulatory balance, a device called iMOBILITY will measure a timed up and go, and strength will be measured with the Biodex machine checking knee flexion and extension. Multiple quality of life and cognitive tests will also be performed. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Accidental Falls
• Parkinson Disease

• NCT number: NCT01119131
• Study type: Interventional
• Source: VA Office of Research and Development
• Status: Completed
• Phase: Phase 2
• Start date: May 2011
• Completion date: January 2015