Parkinson Disease Clinical Trial
Official title:
Effects of Talampanel on Patients With Advanced Parkinson's Disease Who Have Been on Sinemet for More Than 5 Years and Have Dyskinesia (Abnormal Involuntary Movements)
The purpose of this research study is to test the safety and effectiveness of the study
drug, Talampanel, when used to treat patients with involuntary movements known as
dyskinesias, as a result of treatment to Parkinson's disease.
It is not clear why people with Parkinson's disease develop involuntary movements
(dyskinesias) but studies show that blocking receptors in the brain for a chemical called
glutamate decreases these movements. Talampanel is a drug which blocks these receptors.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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