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Influence of Glucose on Metabolism and Clinical Symptoms of Patients With Parkinson's Disease — PaGlu  

Parkinson Disease Clinical Trial

Official title:
Influence of Glucose on Metabolism and Clinical Symptoms of Patients With Parkinson's Disease

Clinical Trial Summary

Many patients with Parkinson's Disease (PD) report an increased consumption of fast-acting sugars. This tendency to consume sweet, high-sugar foods occurs in some patients even before the onset of cardinal motor symptoms. Some recent studies have demonstrated that PD patients have an increased consumption of fast-acting carbohydrates compared to healthy controls. However, the reason for this change in eating behavior has not yet been adequately explained. It is discussed that the increased sugar intake leads to an increased dopamine release in the brain via an increase in insulin and thus to an improvement in clinical symptoms. This study investigates the influence of fast-acting carbohydrates on insulin and glucose blood levels as well as motor and non-motor symptoms in patients with PD using an oral glucose tolerance test and a placebo oral glucose tolerance test in a crossover design.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05998772
Study type Observational
Source University Hospital Schleswig-Holstein
Contact Eva Schäffer, MD
Phone 004943150023983
Email eva.schaeffer@uksh.de
Status Recruiting
Phase
Start date September 1, 2023
Completion date July 2024
View Details
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