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Paresis clinical trials

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NCT ID: NCT06152328 Recruiting - Stroke Clinical Trials

Virtual Reality Based Mirror Therapy

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to examine the effectiveness of 3D virtual reality assisted mirror therapy based rehabilitation applications compared to classical methods used in stroke rehabilitation.

NCT ID: NCT06147167 Not yet recruiting - Stroke Clinical Trials

Effects of Individualized iTBS on Upper Limb Function After Stroke

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The primary objective of this clinical study is to assess the comparative efficacy of individualized intermittent theta burst stimulation (iTBS) in contrast to standard iTBS for individuals post-stroke experiencing upper limb impairment. The key inquiries addressed in this study encompass: Enhancement of Upper Limb Function: The primary investigation seeks to determine whether individualized iTBS yields superior improvements in upper limb functionality compared to standard iTBS. Long-Term Effects: This study endeavors to explore the sustained effects of both individualized and standard iTBS on upper limb function over an extended duration. Neural Mechanisms Investigation: Functional near-infrared spectroscopy (fNIRS) will be employed to elucidate the neural mechanisms underlying the impact of iTBS on the enhancement of upper limb function. Post-stroke individuals with upper limb impairment will undergo pre-treatment assessments, including motor function evaluations and fNIRS tests. Subsequently, they will be randomized into three groups: individualized iTBS, standard iTBS, and sham stimulation. Participants will undergo post-treatment assessments and follow-up evaluations. The research team aims to discern disparities in the efficacy of different iTBS modalities. The central hypothesis posits that individualized iTBS will demonstrate superior efficacy in enhancing post-stroke upper limb function, with sustained effects persisting for a minimum of one month.

NCT ID: NCT06143475 Completed - Stroke Clinical Trials

Functional Proprioceptive Stimulation of the Upper Limbs in Stroke Patients

Start date: February 20, 2021
Phase: N/A
Study type: Interventional

Parallel-group, single-blinded controlled clinical trial. The study involved stroke patients (no more than 3 points on a scale Rankin) dived of the control group and experimental group. Control group received daily sessions of conventional physical therapy. In addition to the same conventional physical therapy treatment, the participants of the experimental group underwent repetitive upper limb Functional Proprioceptive Stimulations (FPS) sessions.

NCT ID: NCT06140862 Active, not recruiting - Clinical trials for Chronic Low-back Pain

Ankle Spine Syndrome "RAFFET Syndrome II

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

A case series aimed to describe a new clinical condition for the first time in the medical literature called Ankle Spine Syndrome or "RAFFET Syndrome II". This syndrome was reported in 6 patients (2 males and 4 females) out of 1000 patients with a history of chronic ankle injuries affecting their calf muscles' strength throughout the last 3 years. The patients suffered from unresolved CLBP with radiculopathy contralateral to their calf muscle atrophy (i.e., an ipsilateral calf muscle weakness induces contralateral lumbar radiculopathy) that did not respond to physical therapy or any medication for long.

NCT ID: NCT06140381 Recruiting - Clinical trials for Hemiparesis;Poststroke/CVA

Strengthening in Sub-acute Stroke Survivors: A Randomized Controlled Trial

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to compare between Eccentric training and conventional therapy in sub-acute stroke survivors. The primary objective of this study is to evaluate improvements in gait speed after four months of ET in comparison to conventional therapy for patients with sub-acute stroke. Secondary objectives involve assessing: i) modifications in neuromuscular parameters of PF, ii) changes in muscle stiffness within PF during passive mobilization and active force generation, and iii) modifications in architectural parameters of PF.

NCT ID: NCT06128616 Not yet recruiting - Cerebral Palsy Clinical Trials

Efficacy of Extracorporeal Shock Wave Therapy in Children With Cerebral Palsy

Start date: November 2023
Phase: Phase 3
Study type: Interventional

Spastic plantar and palmar flexion deformities are very common in children with cerebral palsy (CP). These deformities usually involve spasticity of the plantar or palmar muscle complexes, weakness of the antagonist dorsiflexor muscles of the ankle or wrist, and also involve soft tissue/muscle contractures and require a multimodal treatment approach. Physical therapy (PT), occupational therapy (OT), serial casting (SC), and botulinum toxin A (BoNT-A) injections had shown positive results in both of these deformities. Recent systematic reviews and meta-analyses showed that extracorporeal shock wave therapy (ESWT) is effective in reducing spasticity, pain intensity, and increasing range of motion and motor function when combined with PT or BoNT-A injections in neurological conditions like stroke, CP, multiple sclerosis. ESWT can be a complimentary therapy to obtain an earlier efficacy, better efficacy, a sustained effect for a longer period, and less adverse events. The objective of this study was to show the effects of ESWT when combined with intermittent SC, BoNT-A injections and PT or OT on spasticity, passive range of motion (pROM) of children with CP having spastic equinus foot deformity or wrist palmar flexion deformity.

NCT ID: NCT06126978 Not yet recruiting - Stroke Clinical Trials

The Effect of Vibration Therapy and Mirror Therapy on Upper Limb Function in Patients With Stroke

Start date: November 27, 2023
Phase: N/A
Study type: Interventional

Due to lack of evidence about the difference between the effects of Vibration Therapy and Mirror Therapy on stroke patients, this study aims at comparing the two, in the context of hemiparesis, to help patients improve hand motor functioning and gain occupational recovery. This study applies a two-arm parallel group randomized trial with 36 participants aged 30-65, who had sub-acute stroke 6 months before the study recruitment, and upper limb function deficits of Brunnstrom stage ≥ 3, the spasticity of affected upper extremity score ≤ 2 on the modified Ashworth scale. The participants are outpatients from Jazan Region, Saudi Arabia, and the intervention lasts 4 weeks, with sessions of 35-45 minutes, 3 days per week including the standard conventional therapy. The outcome measurements include Fugl-Meyer Assessment for motor assessment, A Jebsen-Taylor Hand Function Test (JTHFT) objective standardized assessment for activities of daily living (ADLs) and a 30-item Arabic and validated version of Disability of Arm, Shoulder and Hand (DASH) for the upper extremities.

NCT ID: NCT06109194 Recruiting - Clinical trials for Hemiparesis;Poststroke/CVA

Immediate Effect of Ankle Mobilization on Active Range of Motion and Gait in Subacute Stroke

Start date: December 19, 2023
Phase: N/A
Study type: Interventional

The goal of this observational study is to determine the effect of ankle joint mobilization on active range of motion and gait in subacute first-time stroke. The main questions it aims to answer are: - What is the effect of ankle joint mobilization on active range of motion in the ankle and gait qualities? - What is the effect of ankle joint mobilization on self-perceived gait ability? Participants will receive physical therapy interventions of: - Grade III ankle joint mobilization - stretching of ankle plantarflexor muscles - ankle muscle activation training - assisted gait as part of assessment Study design is to measure conditions before and after the intervention to determine effect(s) of one treatment dose, completed within one session of 90 minutes.

NCT ID: NCT06108440 Completed - Stroke Clinical Trials

Comparative Effects of Action Observation and Motor Imagery on Upper Limb in Chronic Stroke Patients

Start date: August 3, 2023
Phase: N/A
Study type: Interventional

To Compare effects of action observation and motor imagery training on upper limb function in chronic stroke patients.

NCT ID: NCT06107556 Not yet recruiting - Stroke Clinical Trials

Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury

NEUROGAIT
Start date: October 19, 2023
Phase:
Study type: Observational

The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.