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An Exploratory Trial to Evaluate Efficacy and Safety for Combination Treatment of Adenovirus Double Suicide Gene Therapy

Pancreas Cancer Clinical Trial

Official title:
A Single Arm, Open, Exploratory Clinical Trial to Evaluate Efficacy and Safety for Combination Treatment of Replication Competent Adenovirus Double Suicide Gene Therapy(Theragene®,Ad5-yCD/mutTKSR39rep-ADP) and Radiation Therapy in Patients

Clinical Trial Summary

Replication-competent Adenovirus-mediated Double Suicide Gene Therapy (Theragene®,Ad5-yCD/mutTKSR39rep-ADP) showed safety and anti-cancer effect in patients with pancreatic cancer in phase I study. From the experience of phase I study, the safety and efficacy of combination with standard chemotherapy and radiation therapy with Theragene treatment will be assessed in this study.

Clinical Trial Description

Phase IIa study of Replication-competent Adenovirus-mediated Double Suicide Gene Therapy (Theragene®,Ad5-yCD/mutTKSR39rep-ADP) with radiation therapy ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04739046
Study type Interventional
Source Seoul National University Bundang Hospital
Contact Jin-Hyeok Hwang, MD PhD
Phone +82-31-787-7017
Email wooltong@snu.ac.kr
Status Recruiting
Phase Phase 2
Start date February 1, 2021
Completion date February 1, 2024
View Details
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