Pancreas Cancer Clinical Trial
Official title:
Early Recovery Outcomes After Standardized Fast-track Whipples Procedure
Today the Whipple procedure is the preferred operation for malignancy in the pancreas. In
abdominal surgery this procedure is known for its high surgical stress-response in the
patient, which has been attempted to be resolved with the introduction of preoperative
high-dose steroids and goal-directed fluid therapy (GDT). Despite this effort, complications
still occur regularly (30%) in the first weeks after the operation here at Rigshospitalet.
Therefore there is still a challenge in the patients who have undergone the Whipple procedure
in the acute postoperative phase. This shows in for example at Rigshospitalet, where 50% of
the patients continue to be in the need of vasoactive medication the morning after the
operation.
Nevertheless, no studies have in detail described the acute (<24h) postoperative phase. There
is also an importance in the fact that there is often no description or control over other
important factors, for example medicine with influence on the circulatory system, fluid
treatment and response to this etc..
The purpose of this study is to investigate what issues or complications, in particular those
of circulatory matter that occurs in this particular group of patients 24 hours after the
operation. Furthermore there is lacking a description of which cause-response- link there can
be between early and later (30 days) complications, as well as when each of these
complications occur. Therefore, there will also be collected data on complications within the
first 30 days after the operation for the purpose of a later secondary publication with the
same authors.
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