"Outcome of Varicocelectomy on Normal Semen in Patients Complaining of Orchialgia

Pain Clinical Trial

Official title:

Outcome of Subinguinal Varicocelectomy on Normal Semen in Patients Complaining of Orchialgia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04509869
• Other study ID #: orchialgia treatment
• Status: Completed
• Phase: N/A
• Start date: August 12, 2017
• Est. completion date: August 12, 2020

Study information

• Verified date: August 2020
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

varicoclelectomy is done for subfertiltiy and varicocele induced orchialgia. The effect of varicocelectomy on semen analysis is controversial. Many articles report favorable outcomes and others do not.

Most study don't focus on varicocelectomy done for varicocele induced orchialgia,and those studies dont report on postoperative semen.

This study will focus on the effect of operation on the semen postoperatively .

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: August 12, 2020
• Est. primary completion date: August 12, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 19 Years to 50 Years

Eligibility

Inclusion Criteria:

1. Primary varicocele

2. Patient's age more than 19 years

3. Normal semen analysis (according to the WHO 5th guide to semen parameters where sperm concentration equal 15 million per ml , total sperm number 40 million per ejaculate ,normal morphology 4 % and motility A =25% or a+b = 32% is considered normal.

4. Scrotal pain after exclusion of other causes.

Exclusion Criteria:

• 1- Recurrent varicocele

Related Conditions & MeSH terms

• Fertility Issues
• Infertility
• Pain
• Varicocele

Intervention

Procedure:
• varicocelectomy
operation for varix ligation

Locations

Country	Name	City	State
Egypt	Assuit Medical School	Assiut	Assuit

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

References & Publications (6)

Abd Ellatif ME, Asker W, Abbas A, Negm A, Al-Katary M, El-Kaffas H, Moatamed A. Varicocelectomy to treat pain, and predictors of success: a prospective study. Curr Urol. 2012 May;6(1):33-6. doi: 10.1159/000338867. Epub 2012 Mar 18. — View Citation

Chen SS. Factors predicting symptomatic relief by varicocelectomy in patients with normospermia and painful varicocele nonresponsive to conservative treatment. Urology. 2012 Sep;80(3):585-9. doi: 10.1016/j.urology.2012.05.014. Epub 2012 Jul 10. — View Citation

Cho CL, Esteves SC, Agarwal A. Indications and outcomes of varicocele repair. Panminerva Med. 2019 Jun;61(2):152-163. doi: 10.23736/S0031-0808.18.03528-0. Review. — View Citation

Maghraby HA. Laparoscopic varicocelectomy for painful varicoceles: merits and outcomes. J Endourol. 2002 Mar;16(2):107-10. — View Citation

Peterson AC, Lance RS, Ruiz HE. Outcomes of varicocele ligation done for pain. J Urol. 1998 May;159(5):1565-7. — View Citation

Yaman O, Ozdiler E, Anafarta K, Gögüs O. Effect of microsurgical subinguinal varicocele ligation to treat pain. Urology. 2000 Jan;55(1):107-8. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	sperm motility	semen analysis will be done preoperative and post-operative	3 months postoperative is our aim
Primary	sperm morphology	semen analysis will be done preoperative and postoperative	3 months postoperative is our aim
Primary	sperm number	semen analysis will be done preoperative and postoperative	3 months postoperative is our aim
Primary	pain of scrotum	subjective sensation measured by visual analogue score preoperative and postoperative	3 months postoperative is our aim