Pain Clinical Trial
Official title:
Acupuncture for the Treatment of Pancreatic Cancer Pain: A Single Arm Phase II Study
RATIONALE: Acupuncture and acupressure may help relieve moderate or severe pain associated
with stage III or stage IV pancreatic cancer.
PURPOSE: Phase II trial to study the effectiveness of acupuncture and accupressure in
treating patients who have moderate or severe pain associated with stage III or stage IV
pancreatic cancer.
OBJECTIVES:
- Assess the effects of acupuncture and acupressure on pain, sedation, and use of opiate
medication in patients with moderate or severe pain related to stage III or IV
pancreatic cancer.
- Determine whether controlled trials of this therapy are warranted in this patient
population.
- Provide data to aid design of further warranted studies of this therapy in this patient
population.
OUTLINE: Patients receive acupuncture treatment comprising 20 minutes of needle insertion
into the arms and abdomen to the depth used in traditional Chinese medicine on approximately
days 4, 7, 11, and 14. After each acupuncture treatment, the acupuncturist applies/reapplies
acupressure devices by inserting 2-6 smaller needles (studs) into the abdomen (which are
held in place with surgical tape) and taping tiny metal balls to 3 points in each ear.
Patients or caregivers are instructed to administer acupressure by pressing on the ear
points (metal balls) for 1-2 minutes per point and moving the semi-permanent abdominal
needles in small circular movements with the fingers, at a rate of 2-3 cycles per second,
for 1-2 minutes per point, upon waking in the morning and in the early afternoon. Patients
or caregivers are also instructed to stimulate a "rescue point" (the Shenmen auricular
point) if patients experience pain exacerbations at other times during the day. Patients who
respond well to acupuncture are offered further treatment.
Pain is assessed using the numerical rating scale on approximately days 1-4, 7, 11, and
14-17. Sedation is assessed using the Profile of Mood States (POMS) on approximately days 3
and 17. Analgesic medication use is assessed on approximately days 1-3 and 15-17.
PROJECTED ACCRUAL: A total of 10-29 patients will be accrued for this study within
approximately 2 years.
;
Primary Purpose: Supportive Care
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT05559255 -
Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI
|
N/A | |
| Terminated |
NCT04356352 -
Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain
|
Phase 2/Phase 3 | |
| Completed |
NCT04748367 -
Leveraging on Immersive Virtual Reality to Reduce Pain and Anxiety in Children During Immunization in Primary Care
|
N/A | |
| Completed |
NCT05057988 -
Virtual Empowered Relief for Chronic Pain
|
N/A | |
| Completed |
NCT04466111 -
Observational, Post Market Study in Treating Chronic Upper Extremity Limb Pain
|
||
| Recruiting |
NCT06206252 -
Can Medical Cannabis Affect Opioid Use?
|
||
| Completed |
NCT05868122 -
A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy
|
Phase 3 | |
| Active, not recruiting |
NCT05006976 -
A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study
|
N/A | |
| Completed |
NCT03273114 -
Cognitive Functional Therapy (CFT) Compared With Core Training Exercise and Manual Therapy (CORE-MT) in Patients With Chronic Low Back Pain
|
N/A | |
| Enrolling by invitation |
NCT06087432 -
Is PNF Application Effective on Temporomandibular Dysfunction
|
N/A | |
| Completed |
NCT05508594 -
Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001
|
Phase 2/Phase 3 | |
| Recruiting |
NCT03646955 -
Partial Breast Versus no Irradiation for Women With Early Breast Cancer
|
N/A | |
| Active, not recruiting |
NCT03472300 -
Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals
|
||
| Completed |
NCT03678168 -
A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries
|
N/A | |
| Completed |
NCT03931772 -
Online Automated Self-Hypnosis Program
|
N/A | |
| Completed |
NCT03286543 -
Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System
|
N/A | |
| Completed |
NCT02913027 -
Can We Improve the Comfort of Pelvic Exams?
|
N/A | |
| Terminated |
NCT02181387 -
Acetaminophen Use in Labor - Does Use of Acetaminophen Reduce Neuraxial Analgesic Drug Requirement During Labor?
|
Phase 4 | |
| Recruiting |
NCT06032559 -
Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment
|
Phase 3 | |
| Active, not recruiting |
NCT03613155 -
Assessment of Anxiety in Patients Treated by SMUR Toulouse and Receiving MEOPA as Part of Their Care
|