Hypoalgesic Effect of Cervical Manipulation

Pain Clinical Trial

Official title:

Hypoalgesic Effects of Specific vs Non-specific Cervical Manipulation in Healthy Subjects

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03541538
• Other study ID #: U1111-1214-1243
• Status: Completed
• Phase: N/A
• Start date: June 20, 2018
• Est. completion date: July 20, 2018

Study information

• Verified date: July 2020
• Source: Universidade Federal de Sao Carlos
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study evaluates the hypoalgesic effect of global and specific cervical joint manipulation in healthy individuals. At first the participants received one of the interventions and after 48 hours, the other.

Description:

Cervical Joint Manipulation (CJM) are often used for pain treatment.

Joint manipulation generates a series of stimuli within the central nervous system through the activation of proprioceptors located in the joint capsule or muscles, stimulates the PAG, causing pain inhibition by activation of non-opioid descending inhibitory pathways.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 21
• Est. completion date: July 20, 2018
• Est. primary completion date: June 20, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• healthy subjects of both sexes

• without pain complaints in the last 90 days

Exclusion Criteria:

• previous spinal surgeries

• spinal canal stenosis

• vertebral fracture

• spondylolisthesis

• cancer

• acute infections

• hemorrhagic disorders

• active tuberculosis

• deep vein thrombosis

• osteoporosis

• rheumatic diseases

• metabolic diseases

• cardiorespiratory diseases

• smoking injury

• musculoskeletal injury

• use of pacemaker

• women in menstrual period

• pregnant women

• use of pain-killers in the last 48 hours

• use of anti-inflammatory drugs in the last 48 hours

• previous joint manipulation treatments

• aversion to cervical joint manipulation

• positivity in the vertebral artery test

• headache in the last seven days

Related Conditions & MeSH terms

• Pain

Intervention

Device:
• Global manipulation
The therapist positioned himself at the head of the stretcher and with one hand supported the side of the participant's face. With the other hand supported the opposite face of the same and then performed contralateral rotation of the cervical and a slight traction to the tissue barrier to perform the manipulation impulse of high speed and short amplitude in rotation. The procedure was carried out bilaterally.
• Especific manipulation
The therapist positioned himself at the head of the stretcher and with one hand kept the middle phalange of the second finger laterally on the articular processes of the C6-7 vertebrae. With the contralateral hand he supported the opposing face of the participant by performing a tilt up to the C6-7 segment and contralateral rotation up to the tissue barrier to carry out the impulse quickly and short. The procedure was carried out bilaterally.

Locations

Country	Name	City	State
Brazil	Ufscar - Universidade Federal de São Carlos	São Carlos	São Paulo

Sponsors (1)

Lead Sponsor	Collaborator
Universidade Federal de Sao Carlos

Country where clinical trial is conducted

Brazil, 

References & Publications (46)

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* Note: There are 46 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pressure Pain Threshold at the posterior region of the forearm	The subjects were placed supine on a stretcher with their elbows fully extended and the anterior portion of the forearm resting on the stretcher. Subjects were instructed to keep their eyes closed during attempts. The examiner used a Somedic Type II digital pressure algometer (Somedic Inc, Hörby, Sweden) on the posterior region of the forearm 10cm below the lateral epicondyle of the elbow towards the third finger, keeping the forearm in pronation. The pressure was then applied perpendicular to the skin at a rate of 40kPa / s using a 1cm2 flat circular probe covered with 1mm of rubber to prevent any skin pain caused by sharp metal edges.	1 minute after the end of the intervention.

External Links

•   La Société Française de Médecine Manuelle
•   Manual Therapy, Posturology & Rehabilitation Journal
•   Science direct
•   Science direct