Pain Clinical Trial
Official title:
Analgesia Requirement and Maternal Satisfaction Following Epidural PCA in Nulliparous Labor: the Effect of a Four-Fold Change in Local Anesthetic Concentration.
This study studies labor epidural analgesia and compares dilute (0.0625%) with concentrated
(0.25%) bupivacaine.
We hypothesize that patients randomize to receive the concentrated drug will require more
drug, will have a more profound motor block, will be more likely to require instrumental
delivery and will be less satisfied than those receiving dilute epidural drugs.
This study examines the effect of two different local anesthetic concentrations used for epidural analgesia in labor. Patients are randomized to receive epidural bupivacaine, either as a concentrated (0.25%), or a dilute (0.0625%) solution, both administered by patient-controlled epidural analgesia (PCEA). ;
Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double-Blind
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