Pain, Postoperative Clinical Trial
Official title:
Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Hip Arthroscopy- a Double-blinded Placebo Controlled RCT
Verified date | September 2023 |
Source | Balgrist University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to assess the effect of Dexamethasone on postoperative pain and nausea after hip arthroscopy.
Status | Completed |
Enrollment | 60 |
Est. completion date | June 30, 2023 |
Est. primary completion date | June 30, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - • Age = 18 years - general anasthesia - Elective isolated unilateral HAS for any reason - No Prior hip surgery - Written informed consent as documented by signature (Appendix Informed Consent Form) - Competent German language skills Exclusion Criteria: - • Chronic pain patient, chronic lower back pain - Steroid or immunosuppressive drugs used within 6 months of surgery - Renal failure, hepatic failure - Relevant allergies - Pregnancy/ Breast feeding - Contraindications for Fortecortin treatment according to Swissmedic - Previous enrollment into the current study - Participation in another study with investigational drug within the 30 days preceding and during the present study - Known or suspected non-compliance, drug or alcohol abuse - Illness according to "Warnings and Precautions of Dexamethasone and NaCl" |
Country | Name | City | State |
---|---|---|---|
Switzerland | Uniklinik Balgrist | Zürich |
Lead Sponsor | Collaborator |
---|---|
Balgrist University Hospital |
Switzerland,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Postoperative pain level | The VAS Pain score assesses pain Levels on a scale from 0 (no pain) to 10 (wost possible pain). | 6 hours postoperatively | |
Primary | Postoperative pain level | The VAS Pain score assesses pain Levels on a scale from 0 (no pain) to 10 (wost possible pain). | 24 hours postoperatively | |
Primary | Amount of opiates (morphinequivalent) consumed | We will assess the amount of Opiates the Patient needed due to the performed Surgery during the hospital stay. | 48 hours postoperatively | |
Primary | Amount of anti-emetics consumed (Ondansetron) | We will assess the amount of mg of anti- emetic drugs (Ondansetron) the Patient required during the Hospital stay. | 48 houts postoperatively | |
Secondary | Patient satisfaction as assessed by the revised American pain society patient outcome questionnaire | Patient satisfaction will be assessed by the revised American pain Society Patient Outcome questionnaire (APS-POQ-R). | 6 hours postoperatively | |
Secondary | Patient satisfaction as assessed by the revised American pain society patient outcome questionnaire | Patient satisfaction will be assessed by the revised American pain Society Patient Outcome questionnaire (APS-POQ-R). | 24 hours postoperatively | |
Secondary | Patient satisfaction as assessed by the revised American pain society patient outcome questionnaire | Patient satisfaction will be assessed by the revised American pain Society Patient Outcome questionnaire (APS-POQ-R). | 48 hours postoperatively | |
Secondary | Number of vomiting events | We will Count the number of vomiting Events postoperatively as a direct marker for postoperative Nausea. | 48 hours postoperatively | |
Secondary | Physical therapy milestones | Our patients will be instructed and perform different postoperative Rehabilitation steps including (first steps in the hallway, Walking up and down stairs, bicycle Ergometer) | 48 hours postoperatively | |
Secondary | Length of hospitalization | The length of hospitalization will be obtained from the Patient Chart. | after 1 week |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05480111 -
The Role of Quadratus Lumborum Blocks Following Minimally Invasive Hysterectomy
|
Phase 4 | |
Completed |
NCT06129305 -
Erector Spina Muscle Distance From the Skin at Different Thoracal Elevations
|
||
Completed |
NCT04401826 -
Micro-surgical Treatment of Gummy Smile
|
N/A | |
Recruiting |
NCT04020133 -
the Role of Popliteal Plexus Block in Pain Management After Anterior Cruciate Ligament Reconstruction.
|
N/A | |
Completed |
NCT03023462 -
Efficacy of an Anterior Quadratus Lumborum Block vs. a TAP-block for Inguinal Hernia Repair
|
N/A | |
Completed |
NCT03546738 -
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
|
N/A | |
Completed |
NCT03652103 -
Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy
|
Phase 4 | |
Terminated |
NCT03261193 -
ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain
|
Phase 3 | |
Withdrawn |
NCT03528343 -
Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy
|
Phase 1/Phase 2 | |
Completed |
NCT02525133 -
Phase 3 Study of Efficacy and Safety of the XaraColl® Bupivacaine Implant After Hernioplasty
|
Phase 3 | |
Completed |
NCT03244540 -
Regional Analgesia After Cesarean Section
|
Phase 4 | |
Enrolling by invitation |
NCT05316168 -
Post Operative Pain Management for ACL Reconstruction
|
Phase 3 | |
Recruiting |
NCT04130464 -
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
|
Phase 4 | |
Enrolling by invitation |
NCT04574791 -
Addition of Muscle Relaxants in a Multimodal Analgesic Regimen for Analgesia After Primary Total Knee Arthroplasty
|
N/A | |
Completed |
NCT04073069 -
Scalp Infiltration With Diprospan Plus Ropivacaine for Postoperative Pain After Craniotomy in Adults
|
Phase 4 | |
Completed |
NCT04526236 -
Influence of Aging on Perioperative Methadone Dosing
|
Phase 4 | |
Recruiting |
NCT05351229 -
Intrathecal Morphine for Analgesia in Video-assisted Thoracic Surgery
|
Phase 4 | |
Enrolling by invitation |
NCT05543109 -
Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block
|
N/A | |
Completed |
NCT05346588 -
THRIVE Feasibility Trial
|
Phase 3 | |
Completed |
NCT04919317 -
Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty
|
Phase 2 |