Standard Bupivacaine vs Liposomal Bupivacaine in Colorectal Patients

Status Terminated

Clinical Trial Summary

The transversus abdominis plane (TAP) block can be used to reduce pain in patients who get abdominal surgery. TAP blocks are given with a local anesthetic. The purpose of this study is to compare pain medication usage after surgery between two different types of local anesthetic: liposomal bupivacaine and standard bupivacaine.

Clinical Trial Description

Pain control is a factor that is central to the surgical patient's postoperative experience. Opioid pain medications are a mainstay of postoperative pain management. However, these have several adverse effects.

Multimodal pain regimens to minimize opioid use have become central to enhanced recovery after surgery (ERAS) protocols. The transversus abdominis plane (TAP) block is one intervention that contributes to this regimen. Traditionally, TAP blocks are performed with local anesthetics such as bupivacaine. More recently, these have also been performed with liposomal bupivacaine, whose duration of action is much greater than regular bupivacaine (96 hours versus 8-9 hours, respectively).

In this study, postoperative opioid usage will be compared between patients receiving regular bupivacaine and liposomal bupivacaine. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03638635
Study type	Interventional
Source	Inova Health Care Services
Contact
Status	Terminated
Phase	Phase 4
Start date	May 14, 2018
Completion date	January 16, 2019

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