Effects of Medium Chain Triglyceride Oil, Versus Olive Oil, for Weight Loss

Overweight Clinical Trial

— Muffin  

Official title:

The Effects of a Weight Loss Diet Containing Medium Chain Triglyceride Oil, Versus Olive Oil, on Body Composition in Free-Living Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00529919
• Other study ID #: F050124003
• Status: Completed
• Phase: N/A
• First received: September 12, 2007
• Last updated: September 12, 2007
• Start date: March 2005
• Est. completion date: June 2007

Study information

• Verified date: September 2007
• Source: University of Alabama at Birmingham
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

The primary aim of this research project is to determine whether the incorporation of food products containing medium chain triglyceride (MCT) oil in a weight-loss program results in a different degree of weight-loss and total and regional fat mass loss than the incorporation of extra light olive oil. The secondary goals are to test whether there are differences in in metabolic risk profile changes between the 2 diets. We hypothesize that men and women who consumed MCT oil as part of their weight loss program will lose more weight and body fat than those who consume olive oil in their weight loss diet.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 53
• Est. completion date: June 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 19 Years to 50 Years

Eligibility

Inclusion Criteria:

• body mass index 27-33 kg/m2

• pre-menopausal women

• weight stable for at least 6 months

• normal score on Brief Symptoms Inventory questionnaire

Exclusion Criteria:

• chronic disease

• weight loss treatment

• medication known to affect body weight

• unstable blood pressure, glucose, lipid levels

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Overweight
• Weight Loss

Intervention

Dietary Supplement:
• Weight loss
Weight loss study including consumption of either 22-25 g of medium chain triglyceride oil or olive oil

Locations

Country	Name	City	State
United States	University of Alabama at Birmingham	Birmingham	Alabama

Sponsors (2)

Lead Sponsor	Collaborator
University of Alabama at Birmingham	International Life Sciences Institute

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in body weight and fat mass, change in plasma lipid concentrations, fasting glucose and fasting insulin		16 weeks
Secondary	Change in blood pressure, change in fat-free mass		16 weeks