Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT05622149 |
Other study ID # |
011638 |
Secondary ID |
|
Status |
Completed |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
March 18, 2016 |
Est. completion date |
October 1, 2016 |
Study information
Verified date |
November 2022 |
Source |
George Washington University |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
The purpose of this study is to determine whether strength training can be used as a viable
exercise modality for the purpose of inducing fat loss.
Description:
Aerobic exercise (AE) is commonly recommended as the most effective exercise modality for
weight loss. The Centers for Disease Control (CDC) recommends 150 minutes of AE for weight
maintenance, and an unspecified greater amount required for weight loss. Similarly, the
American College of Sports Medicine (ACSM) position stand on physical activity for weight
loss recommends 150-250 minutes per week of moderate intensity physical activity. While the
ACSM promotes resistance training (RT) as a means of increasing fat free mass, which should
lead to improved body composition, it does not promote RT for losing significant amounts of
body fat. Similarly, the CDC physical activity guidelines for weight loss do not mention RT
at all as a viable exercise modality for weight loss. This is not surprising, as there is a
paucity of research examining the effects of RT on weight loss. Furthermore, the few studies
that have explored RT for weight loss generally show that it is ineffective. The
effectiveness of any weight loss program is dependent on the size of the caloric deficit that
is created over time, and since AE generally burns more calories per unit of time than RT, it
stands to reason that AE would be the most commonly prescribed type of exercise for weight
loss. Contributing to the exclusion of RT for weight loss is a widespread belief among
dietitians, nutritionists and exercise professionals that it is not possible to induce muscle
growth while in a caloric deficit, and since the creation of a caloric deficit is essential
for fat loss, the use of RT for muscle growth in a caloric deficit is counter intuitive.
However, RT has been shown to elevate resting metabolism for an extended period of time
following cessation of the training session. Additionally, having a greater muscle mass
should lead to a greater resting metabolism. Unlike RT, chronic AE performed in a caloric
deficit (which is often the recommendation for effective weight loss) has the potential to
lead to significant decreases in muscle mass, thereby hampering improvements in body
composition. Ideally, a program designed to improve body composition should do so through fat
losses alone, with muscle mass being maintained or increased.
Several reasons could exist for the lack of effectiveness of RT shown in most studies. These
reasons include, but are not limited to, 1) Body mass being the measured outcome and not body
composition, 2) lack of control and/or measurement of caloric intake, 3) failure to adjust
dietary protein needs to support muscle growth, 4) ineffective RT program design. Case
studies of clients from our lab have routinely shown that profound decreases in bodyfat can
be induced with RT as the exclusive form of exercise. Furthermore, these decreases in bodyfat
occur with concomitant increases in muscle mass, while in a caloric deficit. Therefore, the
specific aims of this proposal are:
1. To determine whether RT combined with dietary intervention (RT+DIET) results in greater
decreases in fat mass than (RT) or dietary intervention (DIET) alone.
2. To determine whether RT combined with dietary intervention (RT+DIET) results in greater
improvements in body composition than (RT) or dietary intervention (DIET) alone.
3. To determine whether concomitant increases in muscle mass and decreases in fat mass can
occur while in a caloric deficit.
The goal of this project is to serve to generate pilot data to determine whether RT can be
used as a viable exercise mode for fat loss and muscle gain. We will then pursue funding for
a subsequent study that compares the effects of RT versus AE on body composition and fat loss
when 1) the caloric intake is monitored to ensure the creation of a caloric deficit, and 2)
dietary protein is appropriately increased to support muscle retention/growth.