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Impact of Beta-3 Agonist on Psychological Distress and Blood Flow of the Bladder in Women With Overactive Bladder Syndrome

Overactive Bladder Syndrome Clinical Trial

Official title:
Far Eastern Memorial Hospital

Clinical Trial Summary

We will get the impact of mirabegron on psychological distress, urethra and bladder blood flow and c reactive protein.

Clinical Trial Description

Background/Purpose: Pharmacologic treatments for female overactive bladder syndrome (OAB) include antimuscarinics and beta-agonist. Similar efficacy has been reported between antimuscarinics and beta-agonist. Antimuscarinics has been found to be beneficial for patients with psychological distress. However, the impact of mirabegron on psychological distress in female OAB remains unknown. In addition, some animal studies found that beta-3 agonist can improve arterial blood flow, bladder ischemia and might improve bladder function; however, there is still lack of human study. Besides, c reactive protein was found to be elevated in female OAB. Nonetheless there is no study mentioning about the impact of mirabegron on c reactive protein. Thus, the aim of this study is to elucidate the impact of mirabegron on psychological distress, bladder blood flow and c reactive protein. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03695822
Study type Interventional
Source Far Eastern Memorial Hospital
Contact
Status Withdrawn
Phase Phase 4
Start date December 24, 2018
Completion date January 31, 2019
View Details
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