Ovarian Reserve Clinical Trial
The purpose of this study is to determine whether ovarian reserve is related to recurrent pregnancy loss
This study will be conducted at the gynecology and infertility department of Kanuni Sultan
Süleyman Training and Research Hospital from 2016 to 2017. The approval of the local
Institutional Review Board (KAEK/2016.22.31) was obtained in June 2016 and informed consents
of all subjects have been prepared. RM is defined as three or more pregnancy losses at <20
weeks of gestation or fetal weight <500 g. Women with history of RM for whom routine workup
for RM (chromosomal analyses of both partners; levels of prolactin and TSH; anticardiolipin
antibody, lupus anticoagulant, antinuclear antibody, and coagulation studies; and pelvic
ultrasonography) is negative are assigned to the RM group. The control group consists of
healthy women with no history of RM who are seeking contraception in the center's family
planning unit. To keep the power of the study at 80% with an alpha-level of 0.05, a sample
size of minumum 60 patients in each group was required.
Demographic data (age,gravidity,parity,pregnancy loss,bmı) ovarian reserve
parameters(AMH,FSH,LH,E2,AFC) will be recorded and then two groups will be compared.
Data will be analyzed with the use of medcalc version 16.4.8 by Gökhan Yıldırım.
Mean,median,SD,lowest and highest frequency ,and ratio values are used at statistical
complementary of data .Quantitative data will be analyzed with the use of the Student t test
and the Mann-Whitney U test. A chisquare test will be used for analyses of qualitative data
;
Observational Model: Cohort, Time Perspective: Cross-Sectional
Status | Clinical Trial | Phase | |
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Recruiting |
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Phase 2 | |
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Withdrawn |
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Enrolling by invitation |
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Completed |
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Phase 3 | |
Completed |
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Impact of Underlying Renal Disease and Immunosuppressive Regimen on Ovarian Reserve in Renal Patients
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Completed |
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Completed |
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Recruiting |
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Phase 4 | |
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Active, not recruiting |
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|
N/A |