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Clinical Trial Summary

Prospective multicentre assay to assess ctDNA value for ovarian cancer monitoring and disease recurrence after front-line treatment.


Clinical Trial Description

The main objective is to explore the capacity of ctDNA to be an early marker of ovarian carcinoma recurrence after front-line treatments, i.e. to show significant modifications before clinical diagnosis of disease relapse.

Prospective multicentre open-label study

During visits in the frame of management of the disease, blood samples will be collected at diagnosis, after each cycle of eventual neoadjuvant chemotherapy, every 6 months during the following 2 years, and every year during the remainin time of follow-up. Tumor samples will be collected at surgery or through a biopsy.

Patients will then have a standard care follow-up for a period of 5 years. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03302884
Study type Interventional
Source Institut Paoli-Calmettes
Contact DOMINIQUE GENRE, MD
Phone 33 4 91 22 37 78
Email drci.up@ipc.unicancer.fr
Status Recruiting
Phase N/A
Start date October 10, 2018
Completion date October 30, 2023

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