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Ovarian Cancer clinical trials

View clinical trials related to Ovarian Cancer.

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NCT ID: NCT06412510 Not yet recruiting - Ovarian Cancer Clinical Trials

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

Start date: June 1, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to see whether participants who are assigned to a multimodal prehabilitation intervention during chemotherapy are able to adhere with exercise and nutrition program to prepare for their cancer surgery.

NCT ID: NCT06412120 Not yet recruiting - Ovarian Cancer Clinical Trials

Study Evaluating Safety, Tolerability, and Metabolism of Niraparib

Start date: September 1, 2024
Phase: Phase 4
Study type: Interventional

The purpose of this study is to identify the genetic characteristic(s), specifically degree of African ancestry, and environmental characteristic(s) that appear to be related to the effects, both good and bad, that the maintenance treatment has women with ovarian cancer. In this study, an investigational medication called niraparib is being tested for the treatment of ovarian cancer. Niraparib works by blocking the ability of cancer cells to fix their genes. Cancer cells with damaged genes have a harder time growing and spreading in the body and can even die.

NCT ID: NCT06403072 Completed - Ovarian Cancer Clinical Trials

(GI-RADS) in Preoperative Evaluation of Adnexal Masses

Start date: June 1, 2021
Phase:
Study type: Observational

prospective study was conducted and performed on 100 women with pelvic pain due to accidently discovered adnexal mass

NCT ID: NCT06399757 Not yet recruiting - Prostate Cancer Clinical Trials

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Start date: May 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors with particular focus on Colorectal carcinoma (CRC).

NCT ID: NCT06395844 Recruiting - Ovarian Cancer Clinical Trials

Safety and Efficacy of Intraperitoneal Injection of METR-NK Cells as Neoadjuvant Therapy for Advanced Epithelial Ovarian Cancer

Start date: May 1, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The goal of this type of clinical trial study is to evaluate the safety and efficacy of metabolic remodeling nature killer cells as neoadjuvant therapy in newly diagnosed patients with advanced ovarian cancer

NCT ID: NCT06395519 Recruiting - Breast Cancer Clinical Trials

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

ERADIC8
Start date: May 2024
Phase: Phase 1
Study type: Interventional

This is a two-part, open-label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and anti- tumor activity of ETX-19477, a novel reversible small molecule inhibitor of PARG.

NCT ID: NCT06394492 Not yet recruiting - Ovarian Cancer Clinical Trials

SHR-A1921 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer

Start date: May 31, 2024
Phase: Phase 3
Study type: Interventional

This study is a randomized, open-label, controlled, phase III study to evaluate the efficacy and safety of SHR-A1921 versus investigator's choice of chemotherapy in patients with platinum-resistant recurrent epithelial ovarian cancer.

NCT ID: NCT06393543 Not yet recruiting - Ovarian Carcinoma Clinical Trials

International Registration of Isolated STIC: to Report and Investigate the Risk of Serous Peritoneal Carcinomatosis

STICRISC
Start date: June 2024
Phase:
Study type: Observational [Patient Registry]

To prospectively assess the incidence of peritoneal carcinomatosis for women with isolated STIC (serous tubal intraepithelial carcinoma). Moreover, to identify histopathological characteristics of STIC which are reproducible and associated to the risk of peritoneal carcinomatosis and to report the findings of additional diagnostics.

NCT ID: NCT06392997 Not yet recruiting - Ovarian Cancer Clinical Trials

Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology

GynRNA
Start date: June 2024
Phase:
Study type: Observational

GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological pathologies by analyzing of coding and non-coding RNA contained in patients saliva. The study population consists of patients with clinically symptomatic females with one or more of the gynecological pathologies (endometriosis, adenomyosis, ovarian cysts, fibroids, ovarian/cervical/uterine cancer) and asymptomatic females. The patients concerned by the study will be managed without modification of the care pathway, nor modification of the therapeutic indications, nor modification of the diagnostic or follow-up examinations necessary according to the context, which are carried out according to the local recommendations.

NCT ID: NCT06390995 Not yet recruiting - Ovarian Cancer Clinical Trials

A Study of TAK-853 in Adult Participants With Folate Receptor Alpha-Positive Advanced Ovarian Cancer And Other Solid Tumors

Start date: May 30, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The main aim of this study are to check for side effects from TAK-853, check how much TAK-853 participants can receive without getting side effects from it, check how well TAK-853 controls symptoms, and to check how much TAK-853 stays in their blood over time. The study will be conducted in two phases including Phase 1 Part and Phase 2 Part. In Phase 1 Part, the participants will stay in the hospital for 3 days at least after their 1st injection for some tests and to check for any side effects from their treatment. In Phase 2 Part, participants will visit their study hospital for multiple times. In both phases, the participants will receive TAK-853 on the first days of each 3-week cycle. The participant will be in the study for about 9 months in Phase 1 Part and for about 24 months in Phase 2 Part. The study doctors will check for side effects from the study treatments.