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Impact of Early Antibiotics on Non-Traumatic Out of Hospital Cardiac Arrest (OHCA)

Out-Of-Hospital Cardiac Arrest Clinical Trial

Official title:
Impact of Early Antibiotics on Non-Traumatic Out of Hospital Cardiac Arrest (OHCA)

Clinical Trial Summary

Specific Aim : The specific aim is to conduct a randomized prospective clinical trial to determine whether no antibiotics in OHCA patients in the ED with very low likelihood of infection is non-inferior to early antibiotic treatment. Hypothesis a: 28-day all-cause mortality will be non-inferior in OHCA patients with very low likelihood of infection who do not receive antibiotic therapy compared with those who receive early antibiotic therapy Hypothesis b: There will be no difference in subsequent incidence of proven infections in the no antibiotics vs, early antibiotics groups Hypothesis c: There will be no difference in the length of ICU stay and overall hospital stay in the early antibiotics vs. no antibiotics groups

Clinical Trial Description

As above ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05914779
Study type Interventional
Source Hamad Medical Corporation
Contact Adeel A Butt, MBBS, MS
Phone +97433311228
Email aabutt@hamad.qa
Status Recruiting
Phase N/A
Start date March 1, 2023
Completion date December 31, 2025
View Details
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