Clinical Trials Logo

Clinical Trial Summary

Investigating the effect of oxytocin on pancreatic endocrine functions by determining insulin and glucagon secretion within physiological ranges of plasma glucose.


Clinical Trial Description

Insulinotropic effects of oxytocin will be examined in 20 healthy men with body mass index (BMI) < 27 kg/m2, during a graded glucose infusion test with concomitant intravenous infusion of synthetic oxytocin or placebo in a randomized, double-blinded design. This will determine the effect of oxytocin on glucose-stimulated insulin and glucagon secretion. Additional changes in plasma/serum concentrations of C-peptide, glucose, glucose-dependent insulinotropic polypeptid (GIP), glucagon-like peptide 1 (GLP-1), and lipids will be assessed. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06334172
Study type Interventional
Source University Hospital, Gentofte, Copenhagen
Contact Vivian Kliim-Hansen, MD
Phone +4524476875
Email vivian.kliim-hansen@regionh.dk
Status Recruiting
Phase N/A
Start date January 1, 2024
Completion date December 31, 2026

See also
  Status Clinical Trial Phase
Completed NCT03859934 - Metabolic Effects of Melatonin Treatment Phase 1
Completed NCT03675360 - Low-Carbohydrate Dietary Pattern on Glycemic Outcomes Trial N/A
Active, not recruiting NCT05618756 - CBD, Nutrient Metabolism and Energy Intake N/A
Completed NCT04791787 - Effect of Ketogenic Diet on Glucose Metabolism and Energy Expenditure in Type 2 Diabetes N/A
Not yet recruiting NCT05910840 - Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care N/A
Completed NCT06095622 - Chickpea Pulao Using Fenugreek Seeds and Indian Rennet for Improving Blood Glycaemic Levels N/A
Completed NCT05719675 - Healthcare Intervention Program on Treatment Adherence in People With Newly Diagnosed Type 2 Diabetes Mellitus. N/A
Recruiting NCT04201600 - Glucose Variability and Cognition in Prediabetes
Active, not recruiting NCT03337828 - Effect of Two Alcohol-free Beers With Different Carbohydrates Composition on Lipids and Glucose Metabolism N/A
Terminated NCT03191201 - A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. Phase 4
Suspended NCT03566511 - Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide Phase 2
Not yet recruiting NCT05764200 - Acute Microbial Switch N/A
Completed NCT04051294 - The Effect of Kombucha on Blood Sugar Levels in Humans N/A
Terminated NCT04938388 - Comparison of Oral Semaglutide w/ Placebo- Treatment for Latino Adults w/T2 Diabetes Receiving Enhanced Lifestyle Care Phase 4
Recruiting NCT04227769 - IL-1-receptor Antagonist During Cephalic Phase of Insulin Secretion in Health and Type 2 Diabetes Phase 2
Completed NCT05581043 - Pre-meals of 3-hydroxybutyrate in Type 2 Diabetes N/A
Completed NCT03671161 - Flash Glucose Measure System and Continuous Subcutaneous Insulin Infusion Therapy in Poorly Controlled Diabetes Type 1 Patients N/A
Active, not recruiting NCT05176197 - Effects of Almonds on Glycemia in Adults With Elevated Hemoglobin A1c Concentrations N/A
Recruiting NCT06260254 - Effects of Railway Vibration on Sleep and Disease N/A
Recruiting NCT05090488 - Integration of Health Coaching and Diabetes Education in Type 2 Diabetes Mellitus Management at Primary Health Care N/A