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Clinical Trial Summary

This is a master protocol designed to evaluate the safety and efficacy of investigational therapies in participants with metastatic castration-resistant prostate cancer (mCRPC).


Clinical Trial Description

This is a master protocol designed to evaluate the safety, tolerability, and maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D) and efficacy of Acapatamab, in combination with enzalutamide, abiraterone, or the PD1 inhibitor AMG 404, AMG 404 monotherapy, as well as Acapatamab monotherapy, in participants with metastatic castration-resistant prostate cancer (mCRPC). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04631601
Study type Interventional
Source Amgen
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date January 15, 2021
Completion date October 23, 2023

See also
  Status Clinical Trial Phase
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