Hypertrophic Obstructive Cardiomyopathy Clinical Trial
Official title:
A Randomised Controlled Pilot Trial: Edge-to-edge Mitral Valve Repair in the Surgical Treatment for Hypertrophic Cardiomyopathy
Objective of the study: to evaluate whether edge-to-edge technique improves clinical and hemodynamic results in patients scheduled to septal myectomy for severely symptomatic hypertrophic obstructive cardiomyopathy.
A randomised controlled pilot trial to evaluate whether edge-to-edge technique improves clinical and hemodynamic results in patients scheduled to septal myectomy for severely symptomatic hypertrophic obstructive cardiomyopathy. Patients with proven hypertrophic cardiomyopathy and resting left ventricle outflow tract obstruction underwent septal myectomy. If patients were suitable for both surgical techniques, they were randomized to septal myectomy + edge-to-edge mitral valve repair or isolated septal myectomy. All surgeons were experienced at least 50 related procedures. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05073094 -
Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy
|
Phase 4 | |
Completed |
NCT05850026 -
Mitral Regurgitation in Hypertrophic Obstructive Cardiomyopathy: Fix it in a Simple, Effective and Durable Way!
|
||
Completed |
NCT04777188 -
Speckle Tracking Echocardiography Analysis of Left Ventricular Myocardium After Percutaneous Intramyocardial Septal Radiofrequency Ablation for Hypertrophic Obstructive Cardiomyopathy
|
N/A | |
Completed |
NCT02054221 -
Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency.
|
N/A | |
Withdrawn |
NCT04905173 -
Comparison of Squat-to-Stand Maneuver With Amyl Nitrite, Valsalva, and Exercise Stress Echocardiography in Inducing Latent Left Ventricular Outflow Obstruction in Hypertrophic Cardiomyopathy
|
N/A | |
Completed |
NCT04066777 -
The Effect of TASH in Patients With HOCM
|
N/A | |
Terminated |
NCT02674958 -
Mobilization of Endothelial Progenitor Cells and Aspirin
|
Phase 3 | |
Not yet recruiting |
NCT04329689 -
Hyp Obst Cardiomyopathy
|
N/A | |
Not yet recruiting |
NCT05025644 -
Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress Test
|
Phase 4 | |
Recruiting |
NCT05257772 -
Electromechanically Optimised Right Ventricular Pacing In Hypertrophic Cardiomyopathy (EMORI-HCM)
|
N/A | |
Recruiting |
NCT04355260 -
The Clinical Research of the Safety and Effectiveness Evaluation for Using Echocardiography-guided Liwen RF Radiofrequency Ablation System to Treat Hypertrophic Obstructive Cardiomyopathy
|
N/A | |
Active, not recruiting |
NCT06003478 -
The Safety and Influencing Factors of Liwen Procedure in The Treatment of Hypertrophic Cardiomyopathy
|
||
Recruiting |
NCT05957419 -
Transapical Beating-Heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy: a Multi-Center Study
|
N/A | |
Recruiting |
NCT02492399 -
Comparisonof Extended Myoectomy and Myoectomy by Morrow in Patients With Hypertrophic Obstructive Cardiomyopathy (HOCM)
|
N/A | |
Completed |
NCT04686487 -
SterEotactic AbLative Radiotherapy in PatiEnts With HypertrophiC ObstrucTive Cardiomyopathy
|
N/A | |
Completed |
NCT05671367 -
Association Between Microvascular Resistance and Outcomes in Patients With Obstructive Hypertrophic Cardiomyopathy
|
||
Completed |
NCT05687487 -
Residual or Recurrent Obstruction After Septal Myectomy
|
||
Enrolling by invitation |
NCT05100420 -
Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository
|
||
Not yet recruiting |
NCT04275544 -
Risk Factors of Postoperative Complications in HCM Patients
|
||
Recruiting |
NCT06167876 -
Safety and Efficacy of Stereotactic Body Radiotherapy in the Treatment of Hypertrophic Obstructive Cardiomyopathy
|
N/A |