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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04463888
Other study ID # B-BR-107-084
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date August 19, 2020
Est. completion date December 31, 2022

Study information

Verified date March 2023
Source National Cheng-Kung University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

In the proposed study, the investigators assumed that high dose of repetitive motor task training using an exoskeleton robot-assisted system may provide benefits in motor shaping and greater brain priming for hand paresis of the stroke patients. Nevertheless, the amount of therapeutic activity with clinicians' guidance is often short of number in therapy sessions.Therefore, using Internet of Things (IoT), connected rehabilitation products and the data they generate that are a new trend of rehabilitation strategy for providing remote home-programs support. The specific aim of this study is to to explore the feasibility of introducing the rental services of a Smart Home-based Exoskeleton Robot System through the IoT business model. And the second purpose is to investigate the effects of applying the exoskeleton robotic device for tenodesisgrip training as a home-based treatment for chronic stroke patients.The expected outcomes of this research are to clarify the feasibility of using IoT business model for launching smart rehabilitation device rental service and the effects of application a high dosage of hand movement training as home program on motor and hand function for patients with chronic stroke.


Recruitment information / eligibility

Status Completed
Enrollment 18
Est. completion date December 31, 2022
Est. primary completion date December 31, 2022
Accepts healthy volunteers No
Gender All
Age group 20 Years to 80 Years
Eligibility Inclusion Criteria: - (1) chronic stroke patients with unilateral cerebral infarction or hemorrhage, (2) computed tomography scan that excluded pathologies other than unilateral cerebral hemisphere injury, (3) capacity to perform a pinch task with the thumb and index finger, (4) no major cognitive or perceptual deficit (i.e., visual, auditory, perceptual, praxis, and memory, as determined using Lowenstein occupational therapy cognitive assessment), (5) premorbid right-handedness and (6) first-ever stroke. Exclusion Criteria: - not meeting inclusion criteria, and with Wernicke's aphasia or global aphasia leading to difficulty of following instruction.

Study Design


Related Conditions & MeSH terms

  • Rehabilitation, Tenodesis, Stroke, Internet of Things
  • Stroke

Intervention

Other:
occupational therapy
occupational therapy targeted to goals that are relevant to the functional needs of the patient

Locations

Country Name City State
Taiwan National Cheng-Kung University Hospital Tainan

Sponsors (1)

Lead Sponsor Collaborator
National Cheng-Kung University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type Measure Description Time frame Safety issue
Primary Change in the result of Box and blocks test The score is the number of blocks carried from one box to the other in one minute. Higher values represent a better outcome. baseline, 4 weeks, 16 weeks and 20 weeks
Secondary Change in the result of Fugl-Meyer assessment for UE motor function Each item is rated on a three-point ordinal scale (2 points for the detail being performed completely, 1 point for the detail being performed partially, and 0 for the detail not being performed). The maximum motor performance score is 66 points for the upper extremity.completely, 1 point for the detail being performed partially, and 0 for the detail not being performed). The maximum motor performance score is 66 points for the upper extremity. baseline, 4 weeks, 16 weeks and 20 weeks
Secondary Change in the result of Modified Ashworth scale (MAS) Muscle tone is defined by the resistance of a muscle being stretched without resistance. baseline, 4 weeks,16 weeks and 20 weeks
Secondary Change in the result of Semmes-Weinstein monofilament (SWM) test The Semmes-Weinstein monofilamenttest examines the cutaneous pressure threshold, range from 1.65-6.65. Higher values represent a worse outcome. baseline, 4 weeks,16 weeks and 20 weeks
Secondary Change in the result of Motor Activity Log MAL is a structured interview with testing sensitivity used to examine how much (amount of use, AOU) and how well (quality of movement, QOM) the subject uses their more-affected arm. For the 30 items MAL, each item is scored on a 0-5-ordinal scale. baseline, 4 weeks,16 weeks and 20 weeks
Secondary Clinical global impression scale Self-reported improvement over the treatment period,. The scale, rated from 1 (very much improved) to 7 (very much worse), is as the indicator for determining perceptible change of the patients for assisted tenodeis-grip robot system. post-intervention (week 4)