Acute Lymphoblastic Leukemia, Pediatric Clinical Trial
Official title:
The Individualized Treatment of 6-mercaptopurine in Children With Acute Lymphoblastic Leukemia in China
The purpose of this study was to assess the efficacy and safety of individualized treatment of 6-mercaptopurine (6-MP) in Chinese children with acute lymphoblastic leukemia, and to investigate the dose-concentration-response (DER) relationship between thiopurine metabolites and adverse events. The individualized administration of 6-MP was established in Chinese children with acute lymphoblastic leukemia.
To inflict minimal pain on the child contributing blood samples, opportunistic sampling design was chosen to collect pharmacokinetic samples. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03676504 -
Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR
|
Phase 1/Phase 2 | |
| Enrolling by invitation |
NCT05622682 -
Vaccine Immune Recovery After Leukemia
|
||
| Not yet recruiting |
NCT05029531 -
Combined Immuno-chemotherapy for Patients With B-linear Acute Lymphoblastic Leukemia Diagnosed From 0 to 365 Days of Life (ALL-Baby-2021)
|
Phase 3 | |
| Not yet recruiting |
NCT06107478 -
Parental Perception of Their Child's Emotional Quality of Life in Paediatric Oncology Before and After "Magic Massages"
|
||
| Recruiting |
NCT05809284 -
Determining the Mechanisms of Loss of CAR T Cell Persistence
|
||
| Recruiting |
NCT04049383 -
CAR-20/19-T Cells in Patients With Relapsed/Refractory B Cell ALL
|
Phase 1 | |
| Active, not recruiting |
NCT04472286 -
Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
|
||
| Completed |
NCT05973032 -
MRD Detection by NGS in Pediatric B-ALL
|
||
| Completed |
NCT05032716 -
EFFECT OF TREADMILL TRAINING ON BALANCE AFTER CHEMOTHERAPY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
|
N/A | |
| Recruiting |
NCT03035344 -
Study of the Intermediate Metabolism in Children With Acute Lymphoblastic Leukemia (ALL)
|
N/A | |
| Terminated |
NCT03705507 -
International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia
|
Phase 1/Phase 2 | |
| Recruiting |
NCT04325841 -
Phase II Study of Anti-CD19 CAR-T Cells Treating Leukemia Children
|
Phase 2 | |
| Active, not recruiting |
NCT03020030 -
Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents
|
Phase 3 | |
| Not yet recruiting |
NCT06257394 -
Treatment of Pediatric Very High-risk Acute Lymphoblastic Leukemia in Korea
|
Phase 2 | |
| Active, not recruiting |
NCT03157323 -
Low GI Diet in Children and Adolescents With ALL
|
N/A | |
| Recruiting |
NCT04996160 -
Palbociclib in Combination With Chemotherapy in Pediatric Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (RELPALL2)
|
Phase 1 | |
| Not yet recruiting |
NCT06421155 -
Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia
|
N/A | |
| Recruiting |
NCT03643276 -
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
|
Phase 3 | |
| Recruiting |
NCT06074666 -
Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence: Study 3
|
N/A | |
| Active, not recruiting |
NCT04088864 -
CD22-CAR T Cells in Children and Young Adults With B Cell Malignancies
|
Phase 1 |