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Clinical Trial Summary

A novel intervention for targeting the treatment of Intraoperative Floppy Iris Syndrome.


Clinical Trial Description

This study explores the effects that medication can have on increasing pupil dilation. Pupil dilation size is important for operative eye procedures. Decreased pupil size is related to increased complication risks in eye surgery. By exploring novel pupil dilation techniques, there is a potential to counteract the effects of poor pupil dilation that is caused by medications such as alpha-blockers. Intraoperative floppy iris syndrome is a syndrome characterized by a floppy iris (IFIS) and poor pupil dilation during surgery that is caused by BPH medications. This study evaluates treatment methods targeting IFIS. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03760185
Study type Interventional
Source Denver Health and Hospital Authority
Contact
Status Completed
Phase Phase 2
Start date January 4, 2019
Completion date September 25, 2020

See also
  Status Clinical Trial Phase
Completed NCT01693575 - Use of APX 100 Device for Small-pupil Cataract Surgery and Intraoperative Floppy-iris Syndrome N/A
Recruiting NCT01070602 - The Effect of Anterior Corneal Incisions on Intraoperative Floppy Iris Syndrome (IFIS) Incidence and Severity in Tamsulosin Treated Cataract Patients N/A
Completed NCT06266962 - Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome Phase 4
Completed NCT01704014 - Intraoperative Floppy Iris Syndrome in Korean Patients Taking α1-Adrenergic Receptor Antagonists N/A
Terminated NCT02093689 - Intraoperative Floppy Iris Syndrome Undergoing Intraocular Lens Replacement Surgery Phase 3
Terminated NCT00627913 - Retrobulbar Injection of Anesthesia Versus Healon 5 in the Management of Intraoperative Floppy Iris Syndrome N/A