The Effects of Phototherapy in Preterm Infants Pda

Patent Ductus Arteriosus After Premature Birth Clinical Trial

Official title: Chest Shielding for Prevention of a Patent Ductus Arteriosus in Preterm Infants Receiving Phototherapy Effect of Phototherapy

Status Active, not recruiting

Clinical Trial Summary

The study was designed to assess whether chest shielding during phototherapy reduces the incidence of PDA, as assessed by serial echocardiographic examinations, in a population of extremely preterm infants born at lower 30 week gestation.

Clinical Trial Description

Phototherapy is a therapeutic intervention frequently used for management of neonatal hyperbilirubinaemia in extremely premature infants, especially in the first week when patency of the ductus is a clinical problem. Phototherapy has also been implicated in increased ductal patency. One randomized, controlled trial showed that chest shielding during phototherapy reduced the incidence and severity of PDA by 50% in preterm infants. These findings were mainly based on clinical evaluation of the ductus with echocardiographic studies performed only on a subgroup of infants noted to have a murmur on clinical examination. ;

Related Conditions & MeSH terms

• Ductus Arteriosus, Patent
• Hyper Bilirubinemia
• Hyperbilirubinemia
• Patent Ductus Arteriosus After Premature Birth
• Premature Birth

• NCT number: NCT03675425
• Study type: Interventional
• Source: Zekai Tahir Burak Women's Health Research and Education Hospital
• Status: Active, not recruiting
• Phase: N/A
• Start date: July 8, 2018
• Completion date: February 28, 2019