Moderate to Severe Plaque Psoriasis Clinical Trial
Official title:
Analysis of the Pathogenesis of Itch in Response to Apremilast Therapy in Psoriasis Patients
This study aims to identify and describe the presence of itch active molecules in psoriasis and response to treatment with apremilast. This data will be complemented by immunohistochemical data determining nerve ending density and neuropeptide concentrations before and during treatment and correlated with patient reported outcome. It is important to underscore that itch may interfere with various aspects of patient functioning, emotions and social status and should therefore be adequately addressed while treating patients with psoriasis
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05020249 -
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Korean Study Participants With Moderate to Severe Plaque Psoriasis
|
Phase 3 | |
| Completed |
NCT01202565 -
Effectiveness of Adalimumab (HUMIRA®) in the Treatment of Scalp and Nail Affection in Patients With Moderate to Severe Plaque Psoriasis in Routine Clinical Practice
|
N/A | |
| Recruiting |
NCT05258331 -
Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of CT303 in Patients With Psoriasis
|
Phase 1 | |
| Recruiting |
NCT04367441 -
Randomized, Double Blinded, Placebo Controlled, Single Dose Escalation Study of 608 in Healthy Subjects
|
Phase 1 | |
| Completed |
NCT01644396 -
An Open-Label, Prospective Study to Assess the Safety and Effectiveness of Adalimumab in Patients With Moderate to Severe Plaque Psoriasis in the Russian Federation
|
Phase 4 | |
| Completed |
NCT01622348 -
Trial of IMO-3100 in Patients With Moderate to Severe Plaque Psoriasis
|
Phase 2 | |
| Recruiting |
NCT04566666 -
To Assess the Effect of SCD-044 Treatment on Moderate to Severe Plaque Psoriasis
|
Phase 2 | |
| Active, not recruiting |
NCT05155098 -
2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness and Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis
|
||
| Recruiting |
NCT06425549 -
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis
|
Phase 3 | |
| Completed |
NCT01555606 -
An Observational Study to Evaluate Patient-Reported Experiences of Living With Moderate-to-Severe Plaque Psoriasis
|
Phase 4 | |
| Completed |
NCT02713295 -
A Study to Provide Real-world Evidence on the Treatment Goal Achievement Rate, Adherence to and Utilization Patterns of Adalimumab in Patients With Moderate to Severe Plaque Psoriasis in Greece
|
||
| Completed |
NCT05342428 -
Safety and Efficacy of TLL018 in Patients With Plaque Psoriasis
|
Phase 1 | |
| Completed |
NCT04967508 -
A Study to Compare SB17 (Proposed Ustekinumab Biosimilar) to Stelara® in Subject With Moderate to Severe Plaque Psoriasis
|
Phase 3 | |
| Completed |
NCT00710580 -
Study Comparing the Efficacy and Safety of ABT-874 to Etanercept and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
|
Phase 3 | |
| Recruiting |
NCT06109818 -
Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ICP-488 in Patients With Moderate to Severe Plaque Psoriasis
|
Phase 2 | |
| Completed |
NCT01077232 -
Documentation of Humira in Psoriasis Patients in Routine Clinical Practice
|
||
| Completed |
NCT03412747 -
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
|
Phase 3 | |
| Withdrawn |
NCT04614298 -
A Phase 4 Study of Brodalumab (KHK4827) in Subjects With Moderate to Severe Plaque Psoriasis
|
Phase 4 | |
| Completed |
NCT02982005 -
A Study of KHK4827 (Brodalumab) in Subjects With Moderate to Severe Psoriasis in Korea
|
Phase 3 | |
| Completed |
NCT00626002 -
Open Label Continuation Study in Moderate to Severe Psoriasis
|
Phase 3 |