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Clinical Trial Summary

Patients aged between 20 and 70 years, ASA physical status I-III, and scheduled for laparoscopic cholecystectomy under general anaesthesia will be enrolled in the study.

Patients will be randomized to the preemptive group to receive an antiemetic regime 1h before the start of surgery or to the intraoperative group to receive the same antiemetic drugs in the same doses intraoperatively, 30 min before the end of surgery.

In the operating room standard monitoring and a standardized anesthetic technique will be implemented in all patients. Nausea, vomiting, retching and PONV (cumulative) will be recorded at PACU, at 4h, 8h and 24h postoperatively. Pain scores assessed by NRS (numerical rating scale) will be recorded at the same time points. Also, when patients received fluids and solid food by mouth will be recorded.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Postoperative Nausea and Vomiting
  • Vomiting

NCT number NCT03023306
Study type Interventional
Source University of Athens
Contact Argyro Fassoulaki, MD PhD DEAA
Phone 306936701333
Email afassou1@otenet.gr
Status Not yet recruiting
Phase N/A
Start date November 2018
Completion date November 2020

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